Apoptosis Database

Description [+]

Synonyms: PMAIP1, NOXA, PHORBOL-12-MYRISTATE-13-ACETATE-INDUCED PROTEIN 1
Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Rodentia; Mus musculus
Short gene description: Phorbol-12-myristate-13-acetate-induced protein 1 (Noxa) [Source:UniProtKB/Swiss-Prot;Acc:Q9JM54]
Family: Bcl-2 family : BH3-only
Process: apoptosis,
Pathways: intrinsic pathway, pre-mitochondrial signaling events,
Criteria: manually curated
Curator comment:
WIKI: PMAIP1-M_musculus

References [+]

Structure & Sequence [+]

Evolution [+]

Gene Ontology [+]

GO id	Name	Ontology type	Evidence
GO:0001836	release of cytochrome c from mitochondria	biological_proccess	IMP
GO:0001844	protein insertion into mitochondrial membrane during induction of apoptosis	biological_proccess	IMP
GO:0006974	response to DNA damage stimulus	biological_proccess	IMP
GO:0008629	induction of apoptosis by intracellular signals	biological_proccess	IMP
GO:0009411	response to UV	biological_proccess	IMP
GO:0010165	response to X-ray	biological_proccess	IMP
GO:0043525	positive regulation of neuron apoptosis	biological_proccess	IMP
GO:0048147	negative regulation of fibroblast proliferation	biological_proccess	IMP
GO:0006915	apoptosis	biological_proccess	ISO
GO:0043065	positive regulation of apoptosis	biological_proccess	IMP
GO:0006917	induction of apoptosis	biological_proccess	IDA
GO:0042981	regulation of apoptosis	biological_proccess	RCA
GO:0005515	protein binding	mollecular_function	IPI
GO:0005739	mitochondrion	cell_component	IDA
GO:0005741	mitochondrial outer membrane	cell_component	EXP

Check GO Evidence Codes here

Information from other databases [+]

PMAIP1 (Mus musculus)