MAPK11 (Homo sapiens)
Description [+]
- Synonyms: MAPK11
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Primates;Hominidae; Homo sapiens
- Short gene description: Mitogen-activated protein kinase 11 (EC 2.7.11.24)(Mitogen-activated protein kinase p38 beta)(MAP kinase p38 beta)(p38b)(p38-2)(Stress-activated protein kinase 2) [Source:UniProtKB/Swiss-Prot;Acc:Q15759]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: MAPK11-H_sapiens
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | Pkinase | 24 | 308 |
PFAM A | Pkinase_Tyr | 24 | 270 |
Protein sequence [+]
MAPK11 | Homo sapiens | 9606 | length:364
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
EIEQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
EIEQ
Structure links:
- Smartdomain prediction information: SM00219
- Smartdomain prediction information: SM00220
- Prosite motif and domain information: PS00107
- Prosite motif and domain information: PS01351
- Profile motif and domain profile information: PS50011
- Interpro domain information: Q15759
- PFAM domain and domain family information: Q15759
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0006468 | protein amino acid phosphorylation | biological_proccess | IEA |
GO:0007265 | Ras protein signal transduction | biological_proccess | EXP |
GO:0006950 | response to stress | biological_proccess | IDA |
GO:0007243 | protein kinase cascade | biological_proccess | IDA |
GO:0004672 | protein kinase activity | mollecular_function | IEA |
GO:0005524 | ATP binding | mollecular_function | IEA |
GO:0004713 | protein tyrosine kinase activity | mollecular_function | IEA |
GO:0004674 | protein serine/threonine kinase activity | mollecular_function | IEA |
GO:0004707 | MAP kinase activity | mollecular_function | IEA |
GO:0005515 | protein binding | mollecular_function | IPI |
GO:0004707 | MAP kinase activity | mollecular_function | TAS |
GO:0000166 | nucleotide binding | mollecular_function | IEA |
GO:0016740 | transferase activity | mollecular_function | IEA |
GO:0008339 | MP kinase activity | mollecular_function | IDA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0005654 | nucleoplasm | cell_component | EXP |
GO:0005829 | cytosol | cell_component | EXP |
GO:0005575 | cellular_component | cell_component | ND |
Check GO Evidence Codes here
Information from other databases [+]
- Gene info from HGNC [?] :6873
- Gene related info from GeneCards [?] : MAPK11
- Ensembl genome browser [?] : ENSG00000185386
- Expression info from Arrayexpress [?] : ENSG00000185386
- Protein expression from Protein Atlas: [?] ENSG00000185386
- Community gene edition from Wikigenes: [?] 5600
- OMIM gene information: 602898
- OMIM disease information:
Click on [?] for more information.