CASP1_HORSE (Equus caballus)
Description [+]
- Synonyms: CASP1_HORSE
- Species: Equus caballus
- Short gene description: Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 subunit p20; Caspase-1 subunit p10]. [Source:UniProtKB/Swiss-Prot;Acc:Q9TV13]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: CASP1_HORSE-E_caballus
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
| Source | Domain Name | Start | End |
|---|---|---|---|
| PFAM A | CARD | 2 | 89 |
| PFAM A | Peptidase_C14 | 163 | 400 |
Protein sequence [+]
CASP1_HORSE | Equus caballus | 9796 | length:404
TGNVLKEKRRLFIRSVGTGTVNSLLDELLEKRVLNQEEMEKVRDENATVMDKARALIDAV
IRKGPQACQIFIGHICEDDPHLAETLRLSSGPQSGNFLKTQDSQAVVHSSPALQAMPDDL
AKLALSGPKVSLKLCSPEVVERIWKEKSAEMYPIMGKSMTRTRLALIICNTEFDNLSRRA
GAEVDIASMKVLLEGLGYSVEVKENLTALDMTTELKAFAARPEHRSSDSTFLVFMSHGIR
EGICGKKFSEKVPDVLEVNTIFQIFNTRNCPNLRDKPKVIIIQACRGENQGVVWLKDSTG
TSGSSSSLAPDDFEDDAIKKAHVEKDFIAFCSSTPDTVSWRSPTTGSVFIEKLIENLQEY
AWSCDLEEIFRKVRLSFELPDARAQMPTAERVTLTRRFYLFPGY
IRKGPQACQIFIGHICEDDPHLAETLRLSSGPQSGNFLKTQDSQAVVHSSPALQAMPDDL
AKLALSGPKVSLKLCSPEVVERIWKEKSAEMYPIMGKSMTRTRLALIICNTEFDNLSRRA
GAEVDIASMKVLLEGLGYSVEVKENLTALDMTTELKAFAARPEHRSSDSTFLVFMSHGIR
EGICGKKFSEKVPDVLEVNTIFQIFNTRNCPNLRDKPKVIIIQACRGENQGVVWLKDSTG
TSGSSSSLAPDDFEDDAIKKAHVEKDFIAFCSSTPDTVSWRSPTTGSVFIEKLIENLQEY
AWSCDLEEIFRKVRLSFELPDARAQMPTAERVTLTRRFYLFPGY
Structure links:
Evolution [+]
Explore tree at phylomeDB: Click here.
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Gene Ontology [+]
| GO id | Name | Ontology type | Evidence |
|---|---|---|---|
| GO:0001666 | response to hypoxia | biological_proccess | IEA |
| GO:0006508 | proteolysis | biological_proccess | IEA |
| GO:0006917 | induction of apoptosis | biological_proccess | IEA |
| GO:0008219 | cell death | biological_proccess | IEA |
| GO:0016485 | protein processing | biological_proccess | IEA |
| GO:0033198 | response to ATP | biological_proccess | IEA |
| GO:0042221 | response to chemical stimulus | biological_proccess | IEA |
| GO:0050715 | positive regulation of cytokine secretion | biological_proccess | IEA |
| GO:0050717 | positive regulation of interleukin-1 alpha secretion | biological_proccess | IEA |
| GO:0050718 | positive regulation of interleukin-1 beta secretion | biological_proccess | IEA |
| GO:0006915 | apoptosis | biological_proccess | IEA |
| GO:0042981 | regulation of apoptosis | biological_proccess | IEA |
| GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB cascade | biological_proccess | IEA |
| GO:0004197 | cysteine-type endopeptidase activity | mollecular_function | IEA |
| GO:0005515 | protein binding | mollecular_function | IEA |
| GO:0008233 | peptidase activity | mollecular_function | IEA |
| GO:0008234 | cysteine-type peptidase activity | mollecular_function | IEA |
| GO:0016787 | hydrolase activity | mollecular_function | IEA |
| GO:0005576 | extracellular region | cell_component | IEA |
| GO:0005622 | intracellular | cell_component | IEA |
| GO:0005737 | cytoplasm | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSECAG00000024367
- Expression info from Arrayexpress [?] : ENSECAG00000024367
- Protein expression from Protein Atlas: [?] ENSECAG00000024367
- Community gene edition from Wikigenes: [?] 100033888
- entrezgene: 100033888
- refseq_peptide: NP_001075311
Click on [?] for more information.
