CASP1_CANFA (Canis lupus familiaris)
Description [+]
- Synonyms: CASP1_CANFA
- Species: Canis lupus familiaris
- Short gene description: Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 subunit p20; Caspase-1 subunit p10]. [Source:UniProtKB/Swiss-Prot;Acc:Q9MZV7]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: CASP1_CANFA-C_familiaris
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | CARD | 42 | 129 |
PFAM A | Peptidase_C14 | 177 | 414 |
Protein sequence [+]
CASP1_CANFA | Canis lupus familiaris | 9615 | length:418
MYSSRQQHGLSLEHILKNGEIARDGKTYVVPIVEGVFVFLTEDKHDKNPFKILETVGKEL
ITGVLHGLLEKDILKLEDAEKKTFYDAKPEDKPWVILNSVRQKRQEAGQALVHTFINTDK
YSTSVEAFVENMPGPTIPDSEESTDTLKLCPPETFVKMYKEKAEEIYPIKERKDRTRLAL
IICNIEFDHLSTRDGAELDIAGMESLLEGLGYSVVVKRKLTAKGMESVLREFAARPEHKS
SDSTFLVLMSHGILNGICGTAHSVENPDVLAYDTIFQIFNNRHCLNLKDKPKVIIIQACR
GENPGELWVSDSPKASTDSWTHQPLMLKSDAIHKVHVEKDFIAFCSSTPHNVSWRHITKG
SLFIAQLITCFQKYSWCCHLEGVFRKVQQSFEKPDVKAQMPTIERVSMTRYFYLFPGN
ITGVLHGLLEKDILKLEDAEKKTFYDAKPEDKPWVILNSVRQKRQEAGQALVHTFINTDK
YSTSVEAFVENMPGPTIPDSEESTDTLKLCPPETFVKMYKEKAEEIYPIKERKDRTRLAL
IICNIEFDHLSTRDGAELDIAGMESLLEGLGYSVVVKRKLTAKGMESVLREFAARPEHKS
SDSTFLVLMSHGILNGICGTAHSVENPDVLAYDTIFQIFNNRHCLNLKDKPKVIIIQACR
GENPGELWVSDSPKASTDSWTHQPLMLKSDAIHKVHVEKDFIAFCSSTPHNVSWRHITKG
SLFIAQLITCFQKYSWCCHLEGVFRKVQQSFEKPDVKAQMPTIERVSMTRYFYLFPGN
Structure links:
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0006508 | proteolysis | biological_proccess | IEA |
GO:0006915 | apoptosis | biological_proccess | IEA |
GO:0042981 | regulation of apoptosis | biological_proccess | IEA |
GO:0043066 | negative regulation of apoptosis | biological_proccess | IEA |
GO:0004197 | cysteine-type endopeptidase activity | mollecular_function | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0008233 | peptidase activity | mollecular_function | IEA |
GO:0008234 | cysteine-type peptidase activity | mollecular_function | IEA |
GO:0016787 | hydrolase activity | mollecular_function | IEA |
GO:0005622 | intracellular | cell_component | IEA |
GO:0005737 | cytoplasm | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSCAFG00000014860
- Expression info from Arrayexpress [?] : ENSCAFG00000014860
- Protein expression from Protein Atlas: [?] ENSCAFG00000014860
- entrezgene: 403724
- refseq_dna: NM_001003125
- refseq_peptide: NP_001003125
Click on [?] for more information.