CASP2 (Canis lupus familiaris)
Description [+]
- Synonyms: CASP2
- Species: Canis lupus familiaris
- Short gene description: Caspase-2 Precursor (CASP-2)(EC 3.4.22.55)(ICH-1 protease)(Neural precursor cell expressed developmentally down-regulated protein 2)(NEDD-2) [Contains Caspase-2 subunit p18;Caspase-2 subunit p13;Caspase-2 subunit p12] [Source:UniProtKB/Swiss-Prot;Acc:P42575]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: CASP2-C_familiaris
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | CARD | 37 | 121 |
PFAM A | Peptidase_C14 | 200 | 445 |
Protein sequence [+]
CASP2 | Canis lupus familiaris | 9615 | length:452
MAAASAGRPAALQRKAPTAAGRGRRILGVCGMHPDHQEALKKNRVVLAKQLLLSELLEHL
LEKDIITLEMREHIQAKVGGFSQNVELLNLLPKRGPQAFDAFCVALRETKQGHLEDLLLT
TLSGLQHGLPPLSCDYDLSLTFPMCESCPPQKQLRLSPDTVEHSLDNGDGPPCLQVKPCT
PEFYQTHYQLAYRLQSRPRGLALVLSNVHFTGEKDLEFRSGGDVDHSTLVTLFKLLGYKV
HVLLDQTAQEMKEKLQNFAQLPAHRVTDSCIVALLSHGVEGGIYGVDGKLLQLQEVFRLF
DNASCPNLQNKPKMFFIQACRGDETDRGVDQQDGKNHTGSSECEESDASKEELLKTRLPT
RSDMICGYACLRGTAAMRNTKRGSWYIEALTQVFSERACDTHVADMLVKVNALIKEREGY
APGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT
LEKDIITLEMREHIQAKVGGFSQNVELLNLLPKRGPQAFDAFCVALRETKQGHLEDLLLT
TLSGLQHGLPPLSCDYDLSLTFPMCESCPPQKQLRLSPDTVEHSLDNGDGPPCLQVKPCT
PEFYQTHYQLAYRLQSRPRGLALVLSNVHFTGEKDLEFRSGGDVDHSTLVTLFKLLGYKV
HVLLDQTAQEMKEKLQNFAQLPAHRVTDSCIVALLSHGVEGGIYGVDGKLLQLQEVFRLF
DNASCPNLQNKPKMFFIQACRGDETDRGVDQQDGKNHTGSSECEESDASKEELLKTRLPT
RSDMICGYACLRGTAAMRNTKRGSWYIEALTQVFSERACDTHVADMLVKVNALIKEREGY
APGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT
Structure links:
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0006508 | proteolysis | biological_proccess | IEA |
GO:0042981 | regulation of apoptosis | biological_proccess | IEA |
GO:0006915 | apoptosis | biological_proccess | IEA |
GO:0051605 | protein maturation via proteolysis | biological_proccess | IEA |
GO:0043065 | positive regulation of apoptosis | biological_proccess | IEA |
GO:0004197 | cysteine-type endopeptidase activity | mollecular_function | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0008234 | cysteine-type peptidase activity | mollecular_function | IEA |
GO:0042802 | identical protein binding | mollecular_function | IEA |
GO:0019904 | protein domain specific binding | mollecular_function | IEA |
GO:0005622 | intracellular | cell_component | IEA |
GO:0005634 | nucleus | cell_component | IEA |
GO:0005737 | cytoplasm | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSCAFG00000003623
- Expression info from Arrayexpress [?] : ENSCAFG00000003623
- Protein expression from Protein Atlas: [?] ENSCAFG00000003623
- entrezgene: 482737
Click on [?] for more information.