FAS (Pongo pygmaeus)

Description [+]

Synonyms: FAS
Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Primates;Hominidae; Pongo pygmaeus
Short gene description: Tumor necrosis factor receptor superfamily member 6 Precursor (FASLG receptor)(Apoptosis-mediating surface antigen FAS)(Apo-1 antigen)(CD95 antigen) [Source:UniProtKB/Swiss-Prot;Acc:P25445]
Family: Null
Process:
Pathways:
Criteria: homology search
Curator comment: Null
WIKI: FAS-P_pygmaeus

Structure & Sequence [+]

Pfam domains: (Pfam is a large collection of protein families.)

Source	Domain Name	Start	End
PFAM A	TNFR_c6	85	127
PFAM A	TNFR_c6	129	165
PFAM A	Death	232	315

Protein sequence [+]

Structure links:

Smartdomain prediction information: SM00208
Smartdomain prediction information: SM00005
Prosite motif and domain information: PS00652

Evolution [+]

Gene Ontology [+]

GO id	Name	Ontology type	Evidence
GO:0007165	signal transduction	biological_proccess	IEA
GO:0006915	apoptosis	biological_proccess	IEA
GO:0006955	immune response	biological_proccess	IEA
GO:0051384	response to glucocorticoid stimulus	biological_proccess	IEA
GO:0009636	response to toxin	biological_proccess	IEA
GO:0048536	spleen development	biological_proccess	IEA
GO:0045619	regulation of lymphocyte differentiation	biological_proccess	IEA
GO:0043066	negative regulation of apoptosis	biological_proccess	IEA
GO:0051260	protein homooligomerization	biological_proccess	IEA
GO:0043065	positive regulation of apoptosis	biological_proccess	IEA
GO:0043029	T cell homeostasis	biological_proccess	IEA
GO:0051789	response to protein stimulus	biological_proccess	IEA
GO:0006924	activation-induced cell death of T cells	biological_proccess	IEA
GO:0008624	induction of apoptosis by extracellular signals	biological_proccess	IEA
GO:0006925	inflammatory cell apoptosis	biological_proccess	IEA
GO:0045060	negative thymic T cell selection	biological_proccess	IEA
GO:0008625	induction of apoptosis via death domain receptors	biological_proccess	IEA
GO:0006927	transformed cell apoptosis	biological_proccess	IEA
GO:0010467	gene expression	biological_proccess	IEA
GO:0002377	immunoglobulin production	biological_proccess	IEA
GO:0003014	renal system process	biological_proccess	IEA
GO:0019724	B cell mediated immunity	biological_proccess	IEA
GO:0045637	regulation of myeloid cell differentiation	biological_proccess	IEA
GO:0050869	negative regulation of B cell activation	biological_proccess	IEA
GO:0005515	protein binding	mollecular_function	IEA
GO:0004872	receptor activity	mollecular_function	IEA
GO:0004888	transmembrane receptor activity	mollecular_function	IEA
GO:0016020	membrane	cell_component	IEA
GO:0005576	extracellular region	cell_component	IEA
GO:0009986	cell surface	cell_component	IEA
GO:0009897	external side of plasma membrane	cell_component	IEA

Check GO Evidence Codes here

Information from other databases [+]