TLR2 (Ornithorhynchus anatinus)
Description [+]
- Synonyms: TLR2
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Prototheria; Ornithorhynchus anatinus
- Short gene description: Toll-like receptor 2 Precursor (Toll/interleukin-1 receptor-like protein 4)(CD282 antigen) [Source:UniProtKB/Swiss-Prot;Acc:O60603]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: TLR2-O_anatinus
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | TIR | 400 | 538 |
Protein sequence [+]
TLR2 | Ornithorhynchus anatinus | 9258 | length:555
QQLDLSKNSIRHVGKTDLQNCVNLKALMLQANQIGTIDEDAFLSLGILELLDLSKNRLSS
LSPSWFQSLSSLLSLNLLYQPHSLQSTQNINHLLLNVTKSDIVLKILSDLTSSKPRNISM
SIPVASPQLKRIELRHVEMTDSWRLEDSRHLQLKRSFELLEYLDLSGNILFDELLKNSAC
DGAWPSLQTLNLSQNSLRYVDQTGASLSTLKKLINLDISQNNNNNLKDFILNLPRLKELY
LSKNKLKTLPEGRLYPNLLVMRISKNALNVFSRKEFESFQKLKALEVGGNNFICSCVFLT
FLQDQQAIASVLTDWPENYICDSPSHVRGQRVQDTHLPLFECHRALLVSVICCILFLIII
LTVALCHHFHGIWYMKMTWAWLQAKRKPRKTQNKEIYFDAFVSYSEEDSYWVENLMVQEL
EHSNPPFRLCLHKRDFVPGKWIIDNIIDSIEKSHKTLFVLSENFVKSEWCKYELDFSHFR
LFDENNDSAILILLEPIEKKAIPQRFCKLRKIMNTKTYLKWPSDETERETFWLNLKSAIK
TEHFIEDSRIAKESA
LSPSWFQSLSSLLSLNLLYQPHSLQSTQNINHLLLNVTKSDIVLKILSDLTSSKPRNISM
SIPVASPQLKRIELRHVEMTDSWRLEDSRHLQLKRSFELLEYLDLSGNILFDELLKNSAC
DGAWPSLQTLNLSQNSLRYVDQTGASLSTLKKLINLDISQNNNNNLKDFILNLPRLKELY
LSKNKLKTLPEGRLYPNLLVMRISKNALNVFSRKEFESFQKLKALEVGGNNFICSCVFLT
FLQDQQAIASVLTDWPENYICDSPSHVRGQRVQDTHLPLFECHRALLVSVICCILFLIII
LTVALCHHFHGIWYMKMTWAWLQAKRKPRKTQNKEIYFDAFVSYSEEDSYWVENLMVQEL
EHSNPPFRLCLHKRDFVPGKWIIDNIIDSIEKSHKTLFVLSENFVKSEWCKYELDFSHFR
LFDENNDSAILILLEPIEKKAIPQRFCKLRKIMNTKTYLKWPSDETERETFWLNLKSAIK
TEHFIEDSRIAKESA
Structure links:
Evolution [+]
Explore tree at phylomeDB:   Click here.
DeathBase uses Jalview, an external application that requires Java. Please, check that you have the latest version of Java
installed and that Java is enabled in your browser. When correctly installed your browser should display the following examples properly. You can download the latest version of Java at Java Download Site.
Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0032760 | positive regulation of tumor necrosis factor production | biological_proccess | IEA |
GO:0032755 | positive regulation of interleukin-6 production | biological_proccess | IEA |
GO:0002238 | response to molecule of fungal origin | biological_proccess | IEA |
GO:0002752 | cell surface pattern recognition receptor signaling pathway | biological_proccess | IEA |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | biological_proccess | IEA |
GO:0042892 | chloramphenicol transport | biological_proccess | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0004888 | transmembrane receptor activity | mollecular_function | IEA |
GO:0042834 | peptidoglycan binding | mollecular_function | IEA |
GO:0051076 | Gram-positive bacterial binding | mollecular_function | IEA |
GO:0016020 | membrane | cell_component | IEA |
GO:0005886 | plasma membrane | cell_component | IEA |
GO:0009897 | external side of plasma membrane | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSOANG00000005291
- Expression info from Arrayexpress [?] : ENSOANG00000005291
- Protein expression from Protein Atlas: [?] ENSOANG00000005291
- entrezgene: 100081248
Click on [?] for more information.