RIPK1 (Ornithorhynchus anatinus)
Description [+]
- Synonyms: RIPK1
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Prototheria; Ornithorhynchus anatinus
- Short gene description: Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1)(Serine/threonine-protein kinase RIP)(Cell death protein RIP)(Receptor-interacting protein) [Source:UniProtKB/Swiss-Prot;Acc:Q13546]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: RIPK1-O_anatinus
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | Pkinase | 17 | 285 |
PFAM A | Pkinase_Tyr | 17 | 285 |
PFAM A | Death | 589 | 674 |
Protein sequence [+]
RIPK1 | Ornithorhynchus anatinus | 9258 | length:676
RSADMSLAKMQISSDDLLEKEQLDSGGFGLVSLCFHRSHGLVVLKNVYTGPQRTEYNASL
LEEGKIMHKLNHSRVVKLLGFILEDGNYSLVMEYMQKGNLMKVLKTDTSIPLSVKGRTIL
EITEGMNYLHGEGVIHKDLKPENILVDDDFHIKIADLGVAAFKTWSKLTKEENNRQRKMK
SAPEAAAGTLFYMAPEHLSSVNTKPTEKSDVYSFAIVLWAIFANKEPYEHAICEQQIYWG
IIHGNRPNVEDIRESCPKEIIDLMEHCWKDHPEDRPTFEGIHQGFSPFYQKHFEKNVETD
VINLKKKYPAPNEIVQRMHSLQIDSTPYRASSTPPDQPNSLHSSQDLGTCYVDDAMFSPY
PENQPVETEAPSEEPSLQQKLQEEANYHLFGERLDKQQSFQNKYSAAQGIEEERKRRVSH
DPFAKAPGPFQTLQPAGARAAAYHGLAGSSVGSQQSAAAGAAPSLPRRGSEPASHSVSFR
TRPAKVPAASTEYGYEPNPGPLFGLHKIPVPETNFDPLANMPTSSYPKSLASIEDLGRIS
ITRSSAIQIGNCNYMMIDDKSLQPASTYLNSQTQLELWAIFENPSSLLDEHLHPVRENLA
KQWKNCARQLGFTEAQIDEIDHDYERDGLKEKVYQMLQKWLMREGNKGATVGKLAKALYE
CKRIDLLNGLIRMVQS
LEEGKIMHKLNHSRVVKLLGFILEDGNYSLVMEYMQKGNLMKVLKTDTSIPLSVKGRTIL
EITEGMNYLHGEGVIHKDLKPENILVDDDFHIKIADLGVAAFKTWSKLTKEENNRQRKMK
SAPEAAAGTLFYMAPEHLSSVNTKPTEKSDVYSFAIVLWAIFANKEPYEHAICEQQIYWG
IIHGNRPNVEDIRESCPKEIIDLMEHCWKDHPEDRPTFEGIHQGFSPFYQKHFEKNVETD
VINLKKKYPAPNEIVQRMHSLQIDSTPYRASSTPPDQPNSLHSSQDLGTCYVDDAMFSPY
PENQPVETEAPSEEPSLQQKLQEEANYHLFGERLDKQQSFQNKYSAAQGIEEERKRRVSH
DPFAKAPGPFQTLQPAGARAAAYHGLAGSSVGSQQSAAAGAAPSLPRRGSEPASHSVSFR
TRPAKVPAASTEYGYEPNPGPLFGLHKIPVPETNFDPLANMPTSSYPKSLASIEDLGRIS
ITRSSAIQIGNCNYMMIDDKSLQPASTYLNSQTQLELWAIFENPSSLLDEHLHPVRENLA
KQWKNCARQLGFTEAQIDEIDHDYERDGLKEKVYQMLQKWLMREGNKGATVGKLAKALYE
CKRIDLLNGLIRMVQS
Structure links:
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0007186 | G-protein coupled receptor protein signaling pathway | biological_proccess | IEA |
GO:0007165 | signal transduction | biological_proccess | IEA |
GO:0006468 | protein amino acid phosphorylation | biological_proccess | IEA |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB cascade | biological_proccess | IEA |
GO:0006917 | induction of apoptosis | biological_proccess | IEA |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | biological_proccess | IEA |
GO:0034612 | response to tumor necrosis factor | biological_proccess | IEA |
GO:0046777 | protein amino acid autophosphorylation | biological_proccess | IEA |
GO:0010940 | positive regulation of necrotic cell death | biological_proccess | IEA |
GO:0060555 | biological_proccess | IEA | |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0004672 | protein kinase activity | mollecular_function | IEA |
GO:0005524 | ATP binding | mollecular_function | IEA |
GO:0004713 | protein tyrosine kinase activity | mollecular_function | IEA |
GO:0004674 | protein serine/threonine kinase activity | mollecular_function | IEA |
GO:0070513 | death domain binding | mollecular_function | IEA |
GO:0005123 | death receptor binding | mollecular_function | IEA |
GO:0016021 | integral to membrane | cell_component | IEA |
GO:0005739 | mitochondrion | cell_component | IEA |
GO:0043235 | receptor complex | cell_component | IEA |
GO:0031264 | death-inducing signaling complex | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSOANG00000014957
- Expression info from Arrayexpress [?] : ENSOANG00000014957
- Protein expression from Protein Atlas: [?] ENSOANG00000014957
Click on [?] for more information.