AIFM3 (Mus musculus)
Description [+]
- Synonyms: AIFM3
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Rodentia; Mus musculus
- Short gene description: apoptosis-inducing factor, mitochondrion-associated 3 Gene [Source:MGI (curated);Acc:Aifm3-001]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: AIFM3-M_musculus
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | Rieske | 68 | 161 |
PFAM A | Pyr_redox | 196 | 298 |
PFAM A | Pyr_redox_2 | 196 | 473 |
PFAM A | Pyr_redox | 334 | 428 |
Protein sequence [+]
Aifm3 | Mus musculus | 10090 | length:605
MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRGYQGNGTARHFHAEERLPTPQP
YPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGV
LSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVTIRASKQALQLQRRTKV
MAKCISPSAGHSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSK
SLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSS
PKTLTCKGKDVENVFTIRTPEDANRVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSV
VELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRAQEGKLQEVVLKSSKVLRA
DVCVLGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRK
VNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDL
EELKFVAFYTKSDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFMLHSKTGDMSWL
TGKGS
YPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGV
LSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVTIRASKQALQLQRRTKV
MAKCISPSAGHSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSK
SLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSS
PKTLTCKGKDVENVFTIRTPEDANRVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSV
VELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRAQEGKLQEVVLKSSKVLRA
DVCVLGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRK
VNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDL
EELKFVAFYTKSDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFMLHSKTGDMSWL
TGKGS
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0006810 | transport | biological_proccess | IEA |
GO:0006915 | apoptosis | biological_proccess | IEA |
GO:0006917 | induction of apoptosis | biological_proccess | ISS |
GO:0008635 | activation of caspase activity by cytochrome c | biological_proccess | ISS |
GO:0022900 | electron transport chain | biological_proccess | IEA |
GO:0045454 | cell redox homeostasis | biological_proccess | IEA |
GO:0051882 | mitochondrial depolarization | biological_proccess | ISS |
GO:0055114 | oxidation reduction | biological_proccess | IEA |
GO:0006917 | induction of apoptosis | biological_proccess | IEA |
GO:0008635 | activation of caspase activity by cytochrome c | biological_proccess | IEA |
GO:0051882 | mitochondrial depolarization | biological_proccess | IEA |
GO:0005506 | iron ion binding | mollecular_function | IEA |
GO:0008656 | caspase activator activity | mollecular_function | ISS |
GO:0009055 | electron carrier activity | mollecular_function | IEA |
GO:0016491 | oxidoreductase activity | mollecular_function | IEA |
GO:0046872 | metal ion binding | mollecular_function | IEA |
GO:0050660 | FAD binding | mollecular_function | IEA |
GO:0051537 | 2 iron, 2 sulfur cluster binding | mollecular_function | IEA |
GO:0051536 | iron-sulfur cluster binding | mollecular_function | IEA |
GO:0008656 | caspase activator activity | mollecular_function | IEA |
GO:0005737 | cytoplasm | cell_component | IEA |
GO:0005739 | mitochondrion | cell_component | ISS |
GO:0005743 | mitochondrial inner membrane | cell_component | ISS |
GO:0005783 | endoplasmic reticulum | cell_component | ISS |
GO:0005739 | mitochondrion | cell_component | IEA |
GO:0005743 | mitochondrial inner membrane | cell_component | IEA |
GO:0005783 | endoplasmic reticulum | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Gene info from MGI [?] MGI:1919418
- Ensembl genome browser [?] : ENSMUSG00000022763
- Expression info from Arrayexpress [?] : ENSMUSG00000022763
- Protein expression from Protein Atlas: [?] ENSMUSG00000022763
- Community gene edition from Wikigenes: [?] 72168
Click on [?] for more information.