HIPK2 (Macaca mulatta)

Description [+]

Synonyms: HIPK2
Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Primates;Cercopithecidae; Macaca mulatta
Short gene description: Homeodomain-interacting protein kinase 2 (hHIPk2)(EC 2.7.11.1) [Source:UniProtKB/Swiss-Prot;Acc:Q9H2X6]
Family: Null
Process:
Pathways:
Criteria: homology search
Curator comment: Null
WIKI: HIPK2-M_mulatta

Structure & Sequence [+]

Pfam domains: (Pfam is a large collection of protein families.)

Source	Domain Name	Start	End
PFAM A	Pkinase	198	526
PFAM A	Pkinase_Tyr	198	424

Protein sequence [+]

Structure links:

Smartdomain prediction information: SM00220
Smartdomain prediction information: SM00219
Prosite motif and domain information: PS00107
Prosite motif and domain information: PS00108

Evolution [+]

Gene Ontology [+]

GO id	Name	Ontology type	Evidence
GO:0006468	protein amino acid phosphorylation	biological_proccess	IEA
GO:0045893	positive regulation of transcription, DNA-dependent	biological_proccess	IEA
GO:0046330	positive regulation of JNK cascade	biological_proccess	IEA
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	biological_proccess	IEA
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	biological_proccess	IEA
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	biological_proccess	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	biological_proccess	IEA
GO:0007628	adult walking behavior	biological_proccess	IEA
GO:0008284	positive regulation of cell proliferation	biological_proccess	IEA
GO:0007179	transforming growth factor beta receptor signaling pathway	biological_proccess	IEA
GO:0009952	anterior/posterior pattern formation	biological_proccess	IEA
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis	biological_proccess	IEA
GO:0007224	smoothened signaling pathway	biological_proccess	IEA
GO:0043388	positive regulation of DNA binding	biological_proccess	IEA
GO:0008344	adult locomotory behavior	biological_proccess	IEA
GO:0043524	negative regulation of neuron apoptosis	biological_proccess	IEA
GO:0050882	voluntary musculoskeletal movement	biological_proccess	IEA
GO:0004672	protein kinase activity	mollecular_function	IEA
GO:0005524	ATP binding	mollecular_function	IEA
GO:0004713	protein tyrosine kinase activity	mollecular_function	IEA
GO:0004674	protein serine/threonine kinase activity	mollecular_function	IEA
GO:0005515	protein binding	mollecular_function	IEA
GO:0046790	virion binding	mollecular_function	IEA
GO:0003714	transcription corepressor activity	mollecular_function	IEA
GO:0005634	nucleus	cell_component	IEA
GO:0016605	PML body	cell_component	IEA
GO:0031965	nuclear membrane	cell_component	IEA
GO:0005813	centrosome	cell_component	IEA
GO:0005737	cytoplasm	cell_component	IEA

Check GO Evidence Codes here

Information from other databases [+]