LTB (Homo sapiens)
Description [+]
- Synonyms: LTB
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Primates;Hominidae; Homo sapiens
- Short gene description: Lymphotoxin-beta (LT-beta)(Tumor necrosis factor C)(TNF-C)(Tumor necrosis factor ligand superfamily member 3) [Source:UniProtKB/Swiss-Prot;Acc:Q06643]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: LTB-H_sapiens
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | TNF | 102 | 243 |
Protein sequence [+]
LTB | Homo sapiens | 9606 | length:244
MGALGLEGRGGRLQGRGSLLLAVAGATSLVTLLLAVPITVLAVLALVPQDQGGLVTETAD
PGAQAQQGLGFQKLPEEEPETDLSPGLPAAHLIGAPLKGQGLGWETTKEQAFLTSGTQFS
DAEGLALPQDGLYYLYCLVGYRGRAPPGGGDPQGRSVTLRSSLYRAGGAYGPGTPELLLE
GAETVTPVLDPARRQGYGPLWYTSVGFGGLVQLRRGERVYVNISHPDMVDFARGKTFFGA
VMVG
PGAQAQQGLGFQKLPEEEPETDLSPGLPAAHLIGAPLKGQGLGWETTKEQAFLTSGTQFS
DAEGLALPQDGLYYLYCLVGYRGRAPPGGGDPQGRSVTLRSSLYRAGGAYGPGTPELLLE
GAETVTPVLDPARRQGYGPLWYTSVGFGGLVQLRRGERVYVNISHPDMVDFARGKTFFGA
VMVG
Structure links:
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0006955 | immune response | biological_proccess | IEA |
GO:0001775 | cell activation | biological_proccess | IEA |
GO:0002037 | negative regulation of L-glutamate transport | biological_proccess | IEA |
GO:0006915 | apoptosis | biological_proccess | IEA |
GO:0008285 | negative regulation of cell proliferation | biological_proccess | IEA |
GO:0009612 | response to mechanical stimulus | biological_proccess | IEA |
GO:0019722 | calcium-mediated signaling | biological_proccess | IEA |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB cascade | biological_proccess | IEA |
GO:0043525 | positive regulation of neuron apoptosis | biological_proccess | IEA |
GO:0045840 | positive regulation of mitosis | biological_proccess | IEA |
GO:0046325 | negative regulation of glucose import | biological_proccess | IEA |
GO:0050806 | positive regulation of synaptic transmission | biological_proccess | IEA |
GO:0051222 | positive regulation of protein transport | biological_proccess | IEA |
GO:0007165 | signal transduction | biological_proccess | TAS |
GO:0007267 | cell-cell signaling | biological_proccess | TAS |
GO:0006917 | induction of apoptosis | biological_proccess | IEA |
GO:0010467 | gene expression | biological_proccess | IEA |
GO:0043588 | skin development | biological_proccess | IEA |
GO:0048535 | lymph node development | biological_proccess | IEA |
GO:0045084 | positive regulation of interleukin-12 biosynthetic process | biological_proccess | ISS |
GO:0005164 | tumor necrosis factor receptor binding | mollecular_function | IEA |
GO:0005125 | cytokine activity | mollecular_function | IEA |
GO:0016020 | membrane | cell_component | IEA |
GO:0005615 | extracellular space | cell_component | IEA |
GO:0016021 | integral to membrane | cell_component | IEA |
GO:0005575 | cellular_component | cell_component | ND |
Check GO Evidence Codes here
KEGG Pathways [+]
Information from other databases [+]
- Gene info from HGNC [?] :6711
- Gene related info from GeneCards [?] : LTB
- Ensembl genome browser [?] : ENSG00000206437
- Expression info from Arrayexpress [?] : ENSG00000206437
- Protein expression from Protein Atlas: [?] ENSG00000206437
- Community gene edition from Wikigenes: [?] 4050
- OMIM gene information: 600978
- OMIM disease information:
Click on [?] for more information.