TP63 (Equus caballus)
Description [+]
- Synonyms: TP63
- Species: Equus caballus
- Short gene description: Tumor protein 63 (p63)(Transformation-related protein 63)(TP63)(Tumor protein p73-like)(p73L)(p51)(p40)(Keratinocyte transcription factor KET)(Chronic ulcerative stomatitis protein)(CUSP) [Source:UniProtKB/Swiss-Prot;Acc:Q9H3D4]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: TP63-E_caballus
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | P53 | 124 | 320 |
PFAM A | P53_tetramer | 352 | 393 |
PFAM A | SAM_2 | 502 | 568 |
Protein sequence [+]
TP63 | Equus caballus | 9796 | length:641
MSQSTQTSEFLSPEVFQHIWDFLEQPICSVQPIDLNFVDEPSENGATNKIEISMDCIRMQ
DSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDAL
SPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPP
PQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDP
ITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRC
FEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDE
LLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSMQSQSSY
GNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGL
SPTQALPPPLSMPSTSHCTPPPPYPTDCSLVSFLARLGCSSCLDYFTTQGLTTIYQIEHY
SMDDLASLKIPEQFRHAIWKGILDHRQLHDFSSPPHLLRTPSGASTVSVGSSETRGERVI
DAVRFTLRQTISFPPRDEWNDFNFDMDARRNKQQRIKEEGE
DSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDAL
SPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPP
PQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDP
ITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRC
FEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDE
LLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSMQSQSSY
GNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGL
SPTQALPPPLSMPSTSHCTPPPPYPTDCSLVSFLARLGCSSCLDYFTTQGLTTIYQIEHY
SMDDLASLKIPEQFRHAIWKGILDHRQLHDFSSPPHLLRTPSGASTVSVGSSETRGERVI
DAVRFTLRQTISFPPRDEWNDFNFDMDARRNKQQRIKEEGE
Structure links:
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0045893 | positive regulation of transcription, DNA-dependent | biological_proccess | IEA |
GO:0006915 | apoptosis | biological_proccess | IEA |
GO:0045892 | negative regulation of transcription, DNA-dependent | biological_proccess | IEA |
GO:0045747 | positive regulation of Notch signaling pathway | biological_proccess | IEA |
GO:0051289 | protein homotetramerization | biological_proccess | IEA |
GO:0030154 | cell differentiation | biological_proccess | IEA |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | biological_proccess | IEA |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | biological_proccess | IEA |
GO:0006917 | induction of apoptosis | biological_proccess | IEA |
GO:0006916 | anti-apoptosis | biological_proccess | IEA |
GO:0009887 | organ morphogenesis | biological_proccess | IEA |
GO:0001501 | skeletal system development | biological_proccess | IEA |
GO:0002064 | epithelial cell development | biological_proccess | IEA |
GO:0031069 | hair follicle morphogenesis | biological_proccess | IEA |
GO:0030326 | embryonic limb morphogenesis | biological_proccess | IEA |
GO:0030855 | epithelial cell differentiation | biological_proccess | IEA |
GO:0001942 | hair follicle development | biological_proccess | IEA |
GO:0042475 | odontogenesis of dentine-containing tooth | biological_proccess | IEA |
GO:0009954 | proximal/distal pattern formation | biological_proccess | IEA |
GO:0048745 | smooth muscle development | biological_proccess | IEA |
GO:0051402 | neuron apoptosis | biological_proccess | IEA |
GO:0008544 | epidermis development | biological_proccess | IEA |
GO:0001736 | establishment of planar polarity | biological_proccess | IEA |
GO:0002053 | positive regulation of mesenchymal cell proliferation | biological_proccess | IEA |
GO:0007389 | pattern specification process | biological_proccess | IEA |
GO:0007499 | ectoderm and mesoderm interaction | biological_proccess | IEA |
GO:0007569 | cell aging | biological_proccess | IEA |
GO:0010259 | multicellular organismal aging | biological_proccess | IEA |
GO:0030850 | prostate gland development | biological_proccess | IEA |
GO:0030859 | polarized epithelial cell differentiation | biological_proccess | IEA |
GO:0035121 | tail morphogenesis | biological_proccess | IEA |
GO:0042771 | DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis | biological_proccess | IEA |
GO:0043589 | skin morphogenesis | biological_proccess | IEA |
GO:0043616 | keratinocyte proliferation | biological_proccess | IEA |
GO:0045617 | negative regulation of keratinocyte differentiation | biological_proccess | IEA |
GO:0048485 | sympathetic nervous system development | biological_proccess | IEA |
GO:0048646 | anatomical structure formation involved in morphogenesis | biological_proccess | IEA |
GO:0048807 | female genitalia morphogenesis | biological_proccess | IEA |
GO:0060157 | urinary bladder development | biological_proccess | IEA |
GO:0060197 | cloacal septation | biological_proccess | IEA |
GO:0030216 | keratinocyte differentiation | biological_proccess | IEA |
GO:0001738 | morphogenesis of a polarized epithelium | biological_proccess | IEA |
GO:0042802 | identical protein binding | mollecular_function | IEA |
GO:0016563 | transcription activator activity | mollecular_function | IEA |
GO:0016564 | transcription repressor activity | mollecular_function | IEA |
GO:0043565 | sequence-specific DNA binding | mollecular_function | IEA |
GO:0003677 | DNA binding | mollecular_function | IEA |
GO:0003684 | damaged DNA binding | mollecular_function | IEA |
GO:0003682 | chromatin binding | mollecular_function | IEA |
GO:0005737 | cytoplasm | cell_component | IEA |
GO:0005634 | nucleus | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSECAG00000018546
- Expression info from Arrayexpress [?] : ENSECAG00000018546
- Protein expression from Protein Atlas: [?] ENSECAG00000018546
- Community gene edition from Wikigenes: [?] 100059752
- entrezgene: 100059752
Click on [?] for more information.