LRP2 (Equus caballus)
Description [+]
- Synonyms: LRP2
- Species: Equus caballus
- Short gene description: Low-density lipoprotein receptor-related protein 2 Precursor (Megalin)(Glycoprotein 330)(gp330) [Source:UniProtKB/Swiss-Prot;Acc:P98164]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: LRP2-E_caballus
Structure & Sequence [+]
Protein sequence [+]
LRP2 | Equus caballus | 9796 | length:4635
ECDSEHFRCENGHCIPASWRCDGTKDCLDDSDETGCPPSSCQSGQFKCQSEGLCIPHSWV
CDDEHDCEDGSDEQHCRGTTCSSDQITCSSGECIPNEFRCDHTRDCSDGTDERDCHYPTC
TQLTCANGACYNISQVCDGKADCRDSSDENNCTKICSQNEFQCGSGECIPHAYLCDHDHD
CEDGSDENSCTYQTCRGNEFTCPSGYCISQDWVCDGEDDCTDNGDEDGCESSTHHIHKCY
PGEWACPGSGKCIPIGKVCDGTLDCPAGEDESNITQGQNCDVNLCPLLGCEYQCHMSPHG
GMCYCPSGFIVDQNSTRNCVDFDDCEIWGICDQMCEDRVGHHQCHCAEGYILEHQRHCKA
NTSSGEASVIFSNGRDLLIGDIHGRTFEMLVQSQNHGVAVGVDFHYHLHRVFWTDTVQDK
VFSVDVNGLHIQEVLNVSVDDPENLAVDWVNNKLYLVETRVNCIEMVNLDGSQRVILITE
NLGHPRGIALDPTVGYLFFSDWESLSGGPKVERAFMDGTNRKDLVKTKLGWPAGITLDMV
SKRVYWVDCRFDYIETVTYDGIQRKTVVHGGSLVPHPFGISLFEDNVFFTDWTKMAVMKA
NKFTETNPETYYRTSLRPFGVTVYHPLRQPYVRNPCGDNNGGCEQICVLSHRTDNDGLGY
RCKCSLGFDMDADERHCVAVKQFLIFSSEVAVRGIPFTLSTQEDVMVPMTGNPSSFVGID
FDAQESTIFFSDTSKDMIFKQKIDGTGREVVTASMVEGVESLSFDWISKNLYWTEASYKS
VSVMRLADKSRREIIKNVNNPRSIVVHPIAGYIFFSDWYRPAKILRAWSDGSNVVPIVNT
TLGWPNGLAIDWGALRLYWVDAFFDKIEHSTFDGSERRALGHIPQMAHPFGLTVFQDYLF
FTDWRLGAIVRVRKTDGGDRTVIRSGISKIMQVKSYDANTQTGSNYCNRPTHPNGDCSHF
CFPVPNLQRVCGCPYGMTLTSNHLTCVEDPSHEPPIEHCGSFSFTCNNGRCVPTYYRCDG
VDDCHDNSDEHLCGTSNNTCSPSAFTCGHGGECIPGHWRCDRHADCVDGSDEQNCPTQTP
TSCPASSFTCDNHHCISRNWVCDTDNDCGDGSDEKDCELPETCLPTQFRCPGHRCIDLSF
VCDGDSDCVDGSDEQACFINCTASQFKCASENRCISNVYHCDGVFDCTDHSDETDCSTRP
SGMCHPDEFQCQADGTCIPGSWECDGHRDCISGSDEHQGCSPRTCPPSHFLCDNGNCVYK
EWLCDGDNDCRDMSDEKDCPTQAFHCPVGQWQCPGHSVCVNLSAVCNGISDCPNGTDESP
LCNQESCSDSNAGCTHQCIQGPFGAQCLCPLGFLLANDSKTCEDIDECEIPGYCSQHCYN
MRGSFRCWCDKEYMLDTDGRTCKVTASESLLLLVASRNQIVADNITSQVHNIYSLIQDGS
HIVAIDFDSVSGRVFWSDGTQGKIWSAFQNGTDKKVVLDSGVTMTESIVVDWVGRHLYWT
NYALETIEVCKLDGSHRTVLISENVTNPRGLALDPRISEHLMFWSDWGHHPRIERASMDG
SLRTVIVQDKIFWPNGLTIDYPNRLLYFMDAYLDYIDFCDYDGQHRRQVIASDLILRHPY
ALTVFEDSVYWTDRATHQVIQANKWHGWNQSVIMYNVYQPLGIVAVHPVKQPHSENSCTF
APCSHLCLLSSEGPHFYSCVCPSGWSLSQDSATCVRDDEPFLIVVRHSIIFGISLNPEVK
SNDAMIPIAGIMNGYDVEFDDSEQFIYWVENPGEIHRVKTDGTNRTIFVPLSRLGSSMSL
ALDWISRNLYYTNPGTQSIEVLTLRGNVRYRKTLITNDGTAFGVGFPIGITVDPANGKLY
WSDQGTDSGVPAKIASANMDGTSSKTLFTGNLEHVEFITLDLQEQKIYWAVTSRGVIERG
NVDGTDRTILVNYLSHPWGIAVHGSFLYYTDEHYEVIERVDKNTGANKVVLRDNIPHLRG
LRVYYKRDAAESSNGCSNNVNACQQICLPVPGGLFSCACATGFKLNPDQQTCSPYESFIV
VSMLSAIRGFNLDLSDHSEAMVPVAGQGRNALHVDVDVSSGFIYWCDFSSSVADYNAIRR
IKPDGSAFMNIVTHGIGENGVRGIALDWVAGNLYFTNAFLSETLIEVLRINTTYRRVLLK
VIVDMPRDIVVDPKNRYLFWADYGQNPKIERSFLDCTNRTVLVSEGIVTPRGLAVDHNNG
YIYWVDDSLDMIARINIEGEESEVIRYGSRYPTPYAITVFEDSIIWVDRNLKKIFKASKE
PDNTELPTVIRDNINWLRDVTIFDKRVQPRSPEAVNNNPCLENNGGCSHLCFALPELHTP
KCGCAFGTLESDGKSCAIPTEHFLVFAMDDSLRSLYLDPENHNPPFQAISVEGIAVDLDY
DSIHNRIYFTHSLSPRHSQISYVNLNSGIVSPTVIVSDIGAADGIAFDWINRRIYYSDYT
NQTINSVAEDGSKRTVIAHVSKPGAIVLDPCRGYMYWTDWDTNAKIERATLGGNFRVPIV
NSSLVWPNGLALDTEEDLLYWADASLLKIERSTLTGLEREVIVSATFHPFGLTLYGQYIY
WTDFSAKKVYRANKYDGSGQMAMTTRFSFEPEGIRVVVKDQQRQCSNPCDEFNGGCSHIC
APGPNGAECQCPHEGRWYLANDNKHCIVDNGTRCDSSKFTCLNGHCISEQWKCDNDNDCG
DGSDELESVCAFHTCPLTAFTCDNGRCVRYHYRCDHYNDCGDNSDEAGCLFRDCNATTEF
TCSNRRCIPLQFVCNGINNCHDNDTSDEKNCPDRTCRPGYIKCQTTNICIPRLYLCDGDN
DCGDMSDESPIFCASQTCSSTEFQCTSGRCIPIHWYCDQERDCSDGSDEPSTCVHDEPTC
LSDEFKCDSGRCIQREWICDGDNDCGDMSDEDERHQCENRSCSGSQFHCVHSTPPSRRCI
PQSWVCDGDADCADGYDEHQNCTRRSCSENEFTCSNGLCVPHSYRCDWRNDCGDYSDERE
CSYPTCNENQFTCQNGICIYKVYTCDGENDCGDDSDELEHLCHTPETTCHPHQFKCDNGN
CIEMVKVCNHLDDCLDNSDEKGCGINECNDASLSGCDQNCTDTLTSFYCSCHPGYKLMSD
KRTCNDIDECKETPFVCSQKCENVIGSYICKCAPGYIREPNGKNCRQNSDIEPYLIFSNR
YYLRNLTTDGHYYSLILQGLGNAVALDFDRVEKRLYWIDRENKVIERMFLNKTNRETVIN
HRLPAAESLAVDWVTRKLYWLDTYLKCLSVSELNGQYRRKLAEHCVDANNTLCFENPRGI
VLHPQYGYVYWADWASRAYIGRVGMDGTNKSVIISTKIVWPNGITIDYTNDLLYWADAHL
GYIEYSDLEGNHRHTVYDGMLPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSDRMVLVN
TTHKPFDIHVYHPYRQPIVNNPCGTNNGGCSHLCLIKAGGKGFTCECPDSFQALRLDDRT
HCLPLCSSTQFLCANNEKCIPIWWKCDGQRDCSDGSDEPTICPPRYCRLGQFQCKDGNCT
SPHFLCNAHEDCPDGSDEDHILCEHHQCESNEWQCANKRCIPEAWQCDSENDCEDNSDED
SSHCARRICQPGYFMCANGRCIPQNWKCDVDNDCGDYSDEPIQECMSAAHRCDNYTEFSC
RTNYRCIPQWAVCNGFNDCRDNSDEQGCEEMTCNPVGDFRCKNHRCIPLRWKCDGHNDCG
DHSDEEDCVPRECTESEFRCGDQSCIPSRQICDHFDDCGDNSDERDCDMRTCHPGYFQCN
SGHCMPDQLKCDGFADCFDSSDEAACPTRFPNGAYCPATEFECKNHVCVQLSWKCDGDDD
CGDGSDEELHLCLNVTCVSPNRFRCDNNRCIYSHELCNQIDDCGDGSDEKKENCADPTPR
PCKEDEFKCSNGHCISQHLVCDDFDDCGDHFDETGCNTGKERSCAENLCEHNCTQLKEGG
FICTCRPGFKASTLDRNSCDDINECEQFGVCPQNCHNTKGSYECSCAQGFKSMGDDYGKR
CAADGNPPLFLLAENVRIRKYNLSSEKYADYLEDEEHIQAIDYDWDPDGIDLSVVYYTVL
GHGSNFGAIKRAYIPNFESENNNIVQEVNLDLKYIAQPDGLAVDWVGRHIYWSDAKSQRI
EVAKLDGRYRKWLISTQLDQPAAVVVNPKLGLMYWTDWGKEPKIESAWMDGQHRIILVKE
DLGWPTGLSIDYLNNDQIYWSDFKENVIETMKHDGTDRRTVVNAAVNPYSLDIFEGELYW
ISKDKGEVWKQDKFGRDEKEKMLVVNPWLTQVRIFQQYRYNQSVPNRCKKVCSHLCLLRP
GGYSCACPQGSTFIAGSITECNAAIESPIMMPPPCRCMHGGNCYFDENDLPKCKCLSGYM
GKYCEAGLSKGVPPGTTVAVLLTVILIIIIGALAMLAFFHYRRTGSLLPALPKLPSLSSL
VKSSENGNGVTFRSGADVNMDIGVSGFGPESAIDRSMVMSEHFAMEMGKQPIIFENPMYT
AKEKDSAVKLNKQAPSICAQVTVSGNVDNRNYGSPINPSEIVPDTQPASPTADGTQATKW
NIFKRKPKQTTNFENPIYAEMDDDQKESGPTAVVPLPSPSPAAEIPSKRSSAPTYTATED
TFKDTANLVREDSEV
CDDEHDCEDGSDEQHCRGTTCSSDQITCSSGECIPNEFRCDHTRDCSDGTDERDCHYPTC
TQLTCANGACYNISQVCDGKADCRDSSDENNCTKICSQNEFQCGSGECIPHAYLCDHDHD
CEDGSDENSCTYQTCRGNEFTCPSGYCISQDWVCDGEDDCTDNGDEDGCESSTHHIHKCY
PGEWACPGSGKCIPIGKVCDGTLDCPAGEDESNITQGQNCDVNLCPLLGCEYQCHMSPHG
GMCYCPSGFIVDQNSTRNCVDFDDCEIWGICDQMCEDRVGHHQCHCAEGYILEHQRHCKA
NTSSGEASVIFSNGRDLLIGDIHGRTFEMLVQSQNHGVAVGVDFHYHLHRVFWTDTVQDK
VFSVDVNGLHIQEVLNVSVDDPENLAVDWVNNKLYLVETRVNCIEMVNLDGSQRVILITE
NLGHPRGIALDPTVGYLFFSDWESLSGGPKVERAFMDGTNRKDLVKTKLGWPAGITLDMV
SKRVYWVDCRFDYIETVTYDGIQRKTVVHGGSLVPHPFGISLFEDNVFFTDWTKMAVMKA
NKFTETNPETYYRTSLRPFGVTVYHPLRQPYVRNPCGDNNGGCEQICVLSHRTDNDGLGY
RCKCSLGFDMDADERHCVAVKQFLIFSSEVAVRGIPFTLSTQEDVMVPMTGNPSSFVGID
FDAQESTIFFSDTSKDMIFKQKIDGTGREVVTASMVEGVESLSFDWISKNLYWTEASYKS
VSVMRLADKSRREIIKNVNNPRSIVVHPIAGYIFFSDWYRPAKILRAWSDGSNVVPIVNT
TLGWPNGLAIDWGALRLYWVDAFFDKIEHSTFDGSERRALGHIPQMAHPFGLTVFQDYLF
FTDWRLGAIVRVRKTDGGDRTVIRSGISKIMQVKSYDANTQTGSNYCNRPTHPNGDCSHF
CFPVPNLQRVCGCPYGMTLTSNHLTCVEDPSHEPPIEHCGSFSFTCNNGRCVPTYYRCDG
VDDCHDNSDEHLCGTSNNTCSPSAFTCGHGGECIPGHWRCDRHADCVDGSDEQNCPTQTP
TSCPASSFTCDNHHCISRNWVCDTDNDCGDGSDEKDCELPETCLPTQFRCPGHRCIDLSF
VCDGDSDCVDGSDEQACFINCTASQFKCASENRCISNVYHCDGVFDCTDHSDETDCSTRP
SGMCHPDEFQCQADGTCIPGSWECDGHRDCISGSDEHQGCSPRTCPPSHFLCDNGNCVYK
EWLCDGDNDCRDMSDEKDCPTQAFHCPVGQWQCPGHSVCVNLSAVCNGISDCPNGTDESP
LCNQESCSDSNAGCTHQCIQGPFGAQCLCPLGFLLANDSKTCEDIDECEIPGYCSQHCYN
MRGSFRCWCDKEYMLDTDGRTCKVTASESLLLLVASRNQIVADNITSQVHNIYSLIQDGS
HIVAIDFDSVSGRVFWSDGTQGKIWSAFQNGTDKKVVLDSGVTMTESIVVDWVGRHLYWT
NYALETIEVCKLDGSHRTVLISENVTNPRGLALDPRISEHLMFWSDWGHHPRIERASMDG
SLRTVIVQDKIFWPNGLTIDYPNRLLYFMDAYLDYIDFCDYDGQHRRQVIASDLILRHPY
ALTVFEDSVYWTDRATHQVIQANKWHGWNQSVIMYNVYQPLGIVAVHPVKQPHSENSCTF
APCSHLCLLSSEGPHFYSCVCPSGWSLSQDSATCVRDDEPFLIVVRHSIIFGISLNPEVK
SNDAMIPIAGIMNGYDVEFDDSEQFIYWVENPGEIHRVKTDGTNRTIFVPLSRLGSSMSL
ALDWISRNLYYTNPGTQSIEVLTLRGNVRYRKTLITNDGTAFGVGFPIGITVDPANGKLY
WSDQGTDSGVPAKIASANMDGTSSKTLFTGNLEHVEFITLDLQEQKIYWAVTSRGVIERG
NVDGTDRTILVNYLSHPWGIAVHGSFLYYTDEHYEVIERVDKNTGANKVVLRDNIPHLRG
LRVYYKRDAAESSNGCSNNVNACQQICLPVPGGLFSCACATGFKLNPDQQTCSPYESFIV
VSMLSAIRGFNLDLSDHSEAMVPVAGQGRNALHVDVDVSSGFIYWCDFSSSVADYNAIRR
IKPDGSAFMNIVTHGIGENGVRGIALDWVAGNLYFTNAFLSETLIEVLRINTTYRRVLLK
VIVDMPRDIVVDPKNRYLFWADYGQNPKIERSFLDCTNRTVLVSEGIVTPRGLAVDHNNG
YIYWVDDSLDMIARINIEGEESEVIRYGSRYPTPYAITVFEDSIIWVDRNLKKIFKASKE
PDNTELPTVIRDNINWLRDVTIFDKRVQPRSPEAVNNNPCLENNGGCSHLCFALPELHTP
KCGCAFGTLESDGKSCAIPTEHFLVFAMDDSLRSLYLDPENHNPPFQAISVEGIAVDLDY
DSIHNRIYFTHSLSPRHSQISYVNLNSGIVSPTVIVSDIGAADGIAFDWINRRIYYSDYT
NQTINSVAEDGSKRTVIAHVSKPGAIVLDPCRGYMYWTDWDTNAKIERATLGGNFRVPIV
NSSLVWPNGLALDTEEDLLYWADASLLKIERSTLTGLEREVIVSATFHPFGLTLYGQYIY
WTDFSAKKVYRANKYDGSGQMAMTTRFSFEPEGIRVVVKDQQRQCSNPCDEFNGGCSHIC
APGPNGAECQCPHEGRWYLANDNKHCIVDNGTRCDSSKFTCLNGHCISEQWKCDNDNDCG
DGSDELESVCAFHTCPLTAFTCDNGRCVRYHYRCDHYNDCGDNSDEAGCLFRDCNATTEF
TCSNRRCIPLQFVCNGINNCHDNDTSDEKNCPDRTCRPGYIKCQTTNICIPRLYLCDGDN
DCGDMSDESPIFCASQTCSSTEFQCTSGRCIPIHWYCDQERDCSDGSDEPSTCVHDEPTC
LSDEFKCDSGRCIQREWICDGDNDCGDMSDEDERHQCENRSCSGSQFHCVHSTPPSRRCI
PQSWVCDGDADCADGYDEHQNCTRRSCSENEFTCSNGLCVPHSYRCDWRNDCGDYSDERE
CSYPTCNENQFTCQNGICIYKVYTCDGENDCGDDSDELEHLCHTPETTCHPHQFKCDNGN
CIEMVKVCNHLDDCLDNSDEKGCGINECNDASLSGCDQNCTDTLTSFYCSCHPGYKLMSD
KRTCNDIDECKETPFVCSQKCENVIGSYICKCAPGYIREPNGKNCRQNSDIEPYLIFSNR
YYLRNLTTDGHYYSLILQGLGNAVALDFDRVEKRLYWIDRENKVIERMFLNKTNRETVIN
HRLPAAESLAVDWVTRKLYWLDTYLKCLSVSELNGQYRRKLAEHCVDANNTLCFENPRGI
VLHPQYGYVYWADWASRAYIGRVGMDGTNKSVIISTKIVWPNGITIDYTNDLLYWADAHL
GYIEYSDLEGNHRHTVYDGMLPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSDRMVLVN
TTHKPFDIHVYHPYRQPIVNNPCGTNNGGCSHLCLIKAGGKGFTCECPDSFQALRLDDRT
HCLPLCSSTQFLCANNEKCIPIWWKCDGQRDCSDGSDEPTICPPRYCRLGQFQCKDGNCT
SPHFLCNAHEDCPDGSDEDHILCEHHQCESNEWQCANKRCIPEAWQCDSENDCEDNSDED
SSHCARRICQPGYFMCANGRCIPQNWKCDVDNDCGDYSDEPIQECMSAAHRCDNYTEFSC
RTNYRCIPQWAVCNGFNDCRDNSDEQGCEEMTCNPVGDFRCKNHRCIPLRWKCDGHNDCG
DHSDEEDCVPRECTESEFRCGDQSCIPSRQICDHFDDCGDNSDERDCDMRTCHPGYFQCN
SGHCMPDQLKCDGFADCFDSSDEAACPTRFPNGAYCPATEFECKNHVCVQLSWKCDGDDD
CGDGSDEELHLCLNVTCVSPNRFRCDNNRCIYSHELCNQIDDCGDGSDEKKENCADPTPR
PCKEDEFKCSNGHCISQHLVCDDFDDCGDHFDETGCNTGKERSCAENLCEHNCTQLKEGG
FICTCRPGFKASTLDRNSCDDINECEQFGVCPQNCHNTKGSYECSCAQGFKSMGDDYGKR
CAADGNPPLFLLAENVRIRKYNLSSEKYADYLEDEEHIQAIDYDWDPDGIDLSVVYYTVL
GHGSNFGAIKRAYIPNFESENNNIVQEVNLDLKYIAQPDGLAVDWVGRHIYWSDAKSQRI
EVAKLDGRYRKWLISTQLDQPAAVVVNPKLGLMYWTDWGKEPKIESAWMDGQHRIILVKE
DLGWPTGLSIDYLNNDQIYWSDFKENVIETMKHDGTDRRTVVNAAVNPYSLDIFEGELYW
ISKDKGEVWKQDKFGRDEKEKMLVVNPWLTQVRIFQQYRYNQSVPNRCKKVCSHLCLLRP
GGYSCACPQGSTFIAGSITECNAAIESPIMMPPPCRCMHGGNCYFDENDLPKCKCLSGYM
GKYCEAGLSKGVPPGTTVAVLLTVILIIIIGALAMLAFFHYRRTGSLLPALPKLPSLSSL
VKSSENGNGVTFRSGADVNMDIGVSGFGPESAIDRSMVMSEHFAMEMGKQPIIFENPMYT
AKEKDSAVKLNKQAPSICAQVTVSGNVDNRNYGSPINPSEIVPDTQPASPTADGTQATKW
NIFKRKPKQTTNFENPIYAEMDDDQKESGPTAVVPLPSPSPAAEIPSKRSSAPTYTATED
TFKDTANLVREDSEV
Evolution [+]
Explore tree at phylomeDB: Click here.
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Gene Ontology [+]
| GO id | Name | Ontology type | Evidence |
|---|---|---|---|
| GO:0008283 | cell proliferation | biological_proccess | IEA |
| GO:0030900 | forebrain development | biological_proccess | IEA |
| GO:0006898 | receptor-mediated endocytosis | biological_proccess | IEA |
| GO:0006766 | vitamin metabolic process | biological_proccess | IEA |
| GO:0005515 | protein binding | mollecular_function | IEA |
| GO:0005768 | endosome | cell_component | IEA |
| GO:0005794 | Golgi apparatus | cell_component | IEA |
| GO:0005783 | endoplasmic reticulum | cell_component | IEA |
| GO:0005624 | membrane fraction | cell_component | IEA |
| GO:0016324 | apical plasma membrane | cell_component | IEA |
| GO:0005903 | brush border | cell_component | IEA |
| GO:0005905 | coated pit | cell_component | IEA |
| GO:0045177 | apical part of cell | cell_component | IEA |
| GO:0030139 | endocytic vesicle | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSECAG00000000435
- Expression info from Arrayexpress [?] : ENSECAG00000000435
- Protein expression from Protein Atlas: [?] ENSECAG00000000435
Click on [?] for more information.
