CASP3_CANFA (Canis lupus familiaris)

Description [+]

Synonyms: CASP3_CANFA
Species: Canis lupus familiaris
Short gene description: Caspase-3 precursor (EC 3.4.22.56) (CASP-3) [Contains: Caspase-3 subunit p17; Caspase-3 subunit p12]. [Source:UniProtKB/Swiss-Prot;Acc:Q8MKI5]
Family: Null
Process:
Pathways:
Criteria: homology search
Curator comment: Null
WIKI: CASP3_CANFA-C_familiaris

Structure & Sequence [+]

Source	Domain Name	Start	End
PFAM A	Peptidase_C14	70	300

Evolution [+]

Gene Ontology [+]

GO id	Name	Ontology type	Evidence
GO:0006508	proteolysis	biological_proccess	IEA
GO:0006915	apoptosis	biological_proccess	IEA
GO:0001782	B cell homeostasis	biological_proccess	IEA
GO:0007507	heart development	biological_proccess	IEA
GO:0006974	response to DNA damage stimulus	biological_proccess	IEA
GO:0006309	DNA fragmentation during apoptosis	biological_proccess	IEA
GO:0006917	induction of apoptosis	biological_proccess	IEA
GO:0007605	sensory perception of sound	biological_proccess	IEA
GO:0045786	negative regulation of cell cycle	biological_proccess	IEA
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	biological_proccess	IEA
GO:0051402	neuron apoptosis	biological_proccess	IEA
GO:0043029	T cell homeostasis	biological_proccess	IEA
GO:0030889	negative regulation of B cell proliferation	biological_proccess	IEA
GO:0045165	cell fate commitment	biological_proccess	IEA
GO:0001836	release of cytochrome c from mitochondria	biological_proccess	IEA
GO:0030216	keratinocyte differentiation	biological_proccess	IEA
GO:0009411	response to UV	biological_proccess	IEA
GO:0008631	induction of apoptosis by oxidative stress	biological_proccess	IEA
GO:0009611	response to wounding	biological_proccess	IEA
GO:0008625	induction of apoptosis via death domain receptors	biological_proccess	IEA
GO:0046007	negative regulation of activated T cell proliferation	biological_proccess	IEA
GO:0043066	negative regulation of apoptosis	biological_proccess	IEA
GO:0030264	nuclear fragmentation during apoptosis	biological_proccess	IEA
GO:0004197	cysteine-type endopeptidase activity	mollecular_function	IEA
GO:0008233	peptidase activity	mollecular_function	IEA
GO:0008234	cysteine-type peptidase activity	mollecular_function	IEA
GO:0016787	hydrolase activity	mollecular_function	IEA
GO:0005515	protein binding	mollecular_function	IEA
GO:0004861	cyclin-dependent protein kinase inhibitor activity	mollecular_function	IEA
GO:0005737	cytoplasm	cell_component	IEA
GO:0005634	nucleus	cell_component	IEA
GO:0005829	cytosol	cell_component	IEA
GO:0005739	mitochondrion	cell_component	IEA

Check GO Evidence Codes here

KEGG Pathways [+]

Information from other databases [+]

Gene related links:

Ensembl genome browser [?] : ENSCAFG00000007750
Expression info from Arrayexpress [?] : ENSCAFG00000007750
Protein expression from Protein Atlas: [?] ENSCAFG00000007750

Protein related links:

Uniprot protein info: Q8MKI5
PIR protein info: Q8MKI5
Protein interactions from IntAct: Q8MKI5

Other links

entrezgene: 403567
refseq_dna: NM_001003042
refseq_peptide: NP_001003042

Click on [?] for more information.