LYN (Canis lupus familiaris)
Description [+]
- Synonyms: LYN
- Species: Canis lupus familiaris
- Short gene description: Tyrosine-protein kinase Lyn (EC 2.7.10.2) [Source:UniProtKB/Swiss-Prot;Acc:P07948]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: LYN-C_familiaris
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | SH3_1 | 61 | 116 |
PFAM A | SH3_2 | 62 | 116 |
PFAM A | SH2 | 124 | 206 |
PFAM A | Pkinase | 242 | 495 |
PFAM A | Pkinase_Tyr | 242 | 492 |
Protein sequence [+]
LYN | Canis lupus familiaris | 9615 | length:507
MGCIKSKRKDNLNDEGIDLKTQPVRNTDRTIYVRDPTSNKQQRPTLPANSPPSQNPEEQG
DIVVALYPYDGIHPDDLSFKKGEKMKVLEELGEWWKAKSLSTKREGFIPSNYVAKVNTLE
TEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSYSLSVRDYDPVHGDVIKHYKI
RSLDNGGYYISPRITFPCISDMIKHYQKQSDGLCRRLEKACISPKPQKPWDKDAWEIPRE
SIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRL
YAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIH
RDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSD
VWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRMENCPDELYDIMKMCWKEKAE
ERPTFDYLQSVLDDFYTATEGQYQQQP
DIVVALYPYDGIHPDDLSFKKGEKMKVLEELGEWWKAKSLSTKREGFIPSNYVAKVNTLE
TEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSYSLSVRDYDPVHGDVIKHYKI
RSLDNGGYYISPRITFPCISDMIKHYQKQSDGLCRRLEKACISPKPQKPWDKDAWEIPRE
SIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRL
YAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIH
RDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSD
VWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRMENCPDELYDIMKMCWKEKAE
ERPTFDYLQSVLDDFYTATEGQYQQQP
Structure links:
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0006468 | protein amino acid phosphorylation | biological_proccess | IEA |
GO:0007242 | intracellular signaling cascade | biological_proccess | IEA |
GO:0008284 | positive regulation of cell proliferation | biological_proccess | IEA |
GO:0018108 | peptidyl-tyrosine phosphorylation | biological_proccess | IEA |
GO:0030218 | erythrocyte differentiation | biological_proccess | IEA |
GO:0009725 | response to hormone stimulus | biological_proccess | IEA |
GO:0050853 | B cell receptor signaling pathway | biological_proccess | IEA |
GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein | biological_proccess | IEA |
GO:0004672 | protein kinase activity | mollecular_function | IEA |
GO:0005524 | ATP binding | mollecular_function | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0004713 | protein tyrosine kinase activity | mollecular_function | IEA |
GO:0004674 | protein serine/threonine kinase activity | mollecular_function | IEA |
GO:0045121 | membrane raft | cell_component | IEA |
GO:0005794 | Golgi apparatus | cell_component | IEA |
GO:0005634 | nucleus | cell_component | IEA |
GO:0005737 | cytoplasm | cell_component | IEA |
Check GO Evidence Codes here
KEGG Pathways [+]
Information from other databases [+]
- Ensembl genome browser [?] : ENSCAFG00000007034
- Expression info from Arrayexpress [?] : ENSCAFG00000007034
- Protein expression from Protein Atlas: [?] ENSCAFG00000007034
- entrezgene: 477886
Click on [?] for more information.