NOD1 (Canis lupus familiaris)
Description [+]
- Synonyms: NOD1
- Species: Canis lupus familiaris
- Short gene description: Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y239]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: NOD1-C_familiaris
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | CARD | 20 | 105 |
PFAM A | NACHT | 196 | 368 |
Protein sequence [+]
NOD1 | Canis lupus familiaris | 9615 | length:953
MEKQSHGEMGIIPSESHSHIKLLKINRELLVTHIRNTQCLVDNLLENDYFSSEDAEIVGA
CPTQPDKVRKILDLVQSKGEEASEFLLYVLQQLEDAYVDLRPWLSEIGFSPSELIQSKVV
VNTDPVSRYTEKLRQQLGRDSKFVLCYAQKEELLLEETYTDTIAELVGLKDESLGPLGSL
ACLLDRSSGVLSEQGETIFICGDAGMGKSMLLQRLQSLWAARRLDAQFKFFFHFRCRVFS
CFKEGDALCLQDLLFKHYCYPEQDPDEVFAFLLRCPHAALFTFDGLDELHSDFDLSGAPD
TSSPWEPAHPLVLLANLLSGKLLKGAAKLLTARTGVEIPRQLLRKKVLLRGFAPSHLRAY
ARRMFPDRTVQQHLLAQLEANPNLCSLCAVPLFCWIIFRCFQHFHSVWDSAAQLPSRTVT
LTDVFLLVTEVHLNRTQPTSLVQRNTRSQVETFRASRGTLRSLGQVAHGGMEKSLFVFGQ
EEVQAAEFQEGELQLGFLRAVPEPGVGGDQQSYEFFHITLQAFFTAFFLVVDDQVGTQQL
LRFFQEWAPPGEAGAESCYPPLLPFQCLKGGGLAGEDPFKNKDHFRFTNLFLCGLLSKAK
EKLLRHLVPPAALRRKRKALWAHLLASLRAHLKNLPRTQSGGFSQVQAMPTFIWMLRCIY
ETQSEKVGRLAAKGICANYLKLTYCNACSADCSALSFVLHHFRKRLALDLDNNNLNDYGV
RELQPCFSRLTVLRLSVNQITDSGVKVLYEELTKYKILTFLGLYSNQITDVGARYVARIL
DECKGLTHLKLGENKITSEGGKCLALAVRNSSSILEIGMWGNRIGDEGAKAFAEALRNHP
SLTNLSLAFNGISTEGGKSLAQALQRNTSLRIFWLTKNELDDEVAESLAEMLKVNQTLKH
LWLIQNQITAKGIAQLADALQKNTGITEICLNGNLIKPEEAKVFEDEKRIVCF
CPTQPDKVRKILDLVQSKGEEASEFLLYVLQQLEDAYVDLRPWLSEIGFSPSELIQSKVV
VNTDPVSRYTEKLRQQLGRDSKFVLCYAQKEELLLEETYTDTIAELVGLKDESLGPLGSL
ACLLDRSSGVLSEQGETIFICGDAGMGKSMLLQRLQSLWAARRLDAQFKFFFHFRCRVFS
CFKEGDALCLQDLLFKHYCYPEQDPDEVFAFLLRCPHAALFTFDGLDELHSDFDLSGAPD
TSSPWEPAHPLVLLANLLSGKLLKGAAKLLTARTGVEIPRQLLRKKVLLRGFAPSHLRAY
ARRMFPDRTVQQHLLAQLEANPNLCSLCAVPLFCWIIFRCFQHFHSVWDSAAQLPSRTVT
LTDVFLLVTEVHLNRTQPTSLVQRNTRSQVETFRASRGTLRSLGQVAHGGMEKSLFVFGQ
EEVQAAEFQEGELQLGFLRAVPEPGVGGDQQSYEFFHITLQAFFTAFFLVVDDQVGTQQL
LRFFQEWAPPGEAGAESCYPPLLPFQCLKGGGLAGEDPFKNKDHFRFTNLFLCGLLSKAK
EKLLRHLVPPAALRRKRKALWAHLLASLRAHLKNLPRTQSGGFSQVQAMPTFIWMLRCIY
ETQSEKVGRLAAKGICANYLKLTYCNACSADCSALSFVLHHFRKRLALDLDNNNLNDYGV
RELQPCFSRLTVLRLSVNQITDSGVKVLYEELTKYKILTFLGLYSNQITDVGARYVARIL
DECKGLTHLKLGENKITSEGGKCLALAVRNSSSILEIGMWGNRIGDEGAKAFAEALRNHP
SLTNLSLAFNGISTEGGKSLAQALQRNTSLRIFWLTKNELDDEVAESLAEMLKVNQTLKH
LWLIQNQITAKGIAQLADALQKNTGITEICLNGNLIKPEEAKVFEDEKRIVCF
Structure links:
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0042981 | regulation of apoptosis | biological_proccess | IEA |
GO:0045449 | regulation of transcription | biological_proccess | IEA |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB cascade | biological_proccess | IEA |
GO:0006917 | induction of apoptosis | biological_proccess | IEA |
GO:0006919 | activation of caspase activity | biological_proccess | IEA |
GO:0007242 | intracellular signaling cascade | biological_proccess | IEA |
GO:0016045 | detection of bacterium | biological_proccess | IEA |
GO:0042228 | interleukin-8 biosynthetic process | biological_proccess | IEA |
GO:0032760 | positive regulation of tumor necrosis factor production | biological_proccess | IEA |
GO:0032755 | positive regulation of interleukin-6 production | biological_proccess | IEA |
GO:0032874 | positive regulation of stress-activated MAPK cascade | biological_proccess | IEA |
GO:0046330 | positive regulation of JNK cascade | biological_proccess | IEA |
GO:0050830 | defense response to Gram-positive bacterium | biological_proccess | IEA |
GO:0070374 | positive regulation of ERK1 and ERK2 cascade | biological_proccess | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0000166 | nucleotide binding | mollecular_function | IEA |
GO:0017111 | nucleoside-triphosphatase activity | mollecular_function | IEA |
GO:0005523 | tropomyosin binding | mollecular_function | IEA |
GO:0005524 | ATP binding | mollecular_function | IEA |
GO:0030528 | transcription regulator activity | mollecular_function | IEA |
GO:0042802 | identical protein binding | mollecular_function | IEA |
GO:0050700 | CARD domain binding | mollecular_function | IEA |
GO:0005622 | intracellular | cell_component | IEA |
GO:0005856 | cytoskeleton | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSCAFG00000003074
- Expression info from Arrayexpress [?] : ENSCAFG00000003074
- Protein expression from Protein Atlas: [?] ENSCAFG00000003074
- entrezgene: 482382
Click on [?] for more information.