TNR1A_BOVIN (Bos taurus)

Description [+]

Synonyms: TNR1A_BOVIN
Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Ruminantia; Bos taurus
Short gene description: Tumor necrosis factor receptor superfamily member 1A Precursor (p60)(TNF-R1)(TNF-RI)(TNFR-I)(p55)(CD120a antigen) [Source:UniProtKB/Swiss-Prot;Acc:O19131]
Family: Null
Process:
Pathways:
Criteria: homology search
Curator comment: Null
WIKI: TNR1A_BOVIN-B_taurus

Structure & Sequence [+]

Pfam domains: (Pfam is a large collection of protein families.)

Source	Domain Name	Start	End
PFAM A	TNFR_c6	44	81
PFAM A	TNFR_c6	84	125
PFAM A	TNFR_c6	127	166
PFAM A	Death	373	457

Protein sequence [+]

Structure links:

Smartdomain prediction information: SM00208
Smartdomain prediction information: SM00005
Prosite motif and domain information: PS00652
Prosite motif and domain information: PS01186
Interpro domain information: O19131
PFAM domain and domain family information: O19131

Evolution [+]

Gene Ontology [+]

GO id	Name	Ontology type	Evidence
GO:0050729	positive regulation of inflammatory response	biological_proccess	ISS
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	biological_proccess	ISS
GO:0019221	cytokine-mediated signaling pathway	biological_proccess	ISS
GO:0007166	cell surface receptor linked signal transduction	biological_proccess	ISS
GO:0006954	inflammatory response	biological_proccess	ISS
GO:0006952	defense response	biological_proccess	ISS
GO:0006693	prostaglandin metabolic process	biological_proccess	ISS
GO:0006915	apoptosis	biological_proccess	IEA
GO:0007165	signal transduction	biological_proccess	IEA
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	biological_proccess	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	biological_proccess	IEA
GO:0006954	inflammatory response	biological_proccess	IEA
GO:0006952	defense response	biological_proccess	IEA
GO:0019221	cytokine-mediated signaling pathway	biological_proccess	IEA
GO:0007166	cell surface receptor linked signal transduction	biological_proccess	IEA
GO:0050729	positive regulation of inflammatory response	biological_proccess	IEA
GO:0009816	defense response to bacterium, incompatible interaction	biological_proccess	IEA
GO:0005031	tumor necrosis factor receptor activity	mollecular_function	ISS
GO:0004872	receptor activity	mollecular_function	IEA
GO:0005515	protein binding	mollecular_function	IEA
GO:0005031	tumor necrosis factor receptor activity	mollecular_function	IEA
GO:0016020	membrane	cell_component	IEA
GO:0016021	integral to membrane	cell_component	IEA
GO:0045121	membrane raft	cell_component	IEA

Check GO Evidence Codes here

KEGG Pathways [+]

Information from other databases [+]

Gene related links:

Ensembl genome browser [?] : ENSBTAG00000004211
Expression info from Arrayexpress [?] : ENSBTAG00000004211
Protein expression from Protein Atlas: [?] ENSBTAG00000004211

Protein related links:

Uniprot protein info: O19131
PIR protein info: O19131
Protein interactions from IntAct: O19131

Other links

entrezgene: 282527
refseq_dna: NM_174674
refseq_peptide: NP_777099

Click on [?] for more information.