10        20        30        40        50        60        70        80        90       100       110       120
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000376849                 --------------------------------------------------------------------------------------------------------AVPRVEGVFIFLIEDS
P_troglodytes_ENSPTRP00000007279          --------------------------------------------------------------------------------------------------------AVPRVEGVFIFLIEDS
P_pygmaeus_ENSPPYP00000004374             --------------------------------------------------------------------------------------------------------AVPIVEGVFIFLIEDS
G_gorilla_ENSGGOP00000015374              ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000012894              ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000041705          ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000004373             ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000347741                 ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000027820               ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000012893              ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000031565           ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000010831             ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000027012             ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000058685           ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000004377             ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000260309                 ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000006810             ------------------------------------------------------------------------------------------------------------------------
O_anatinus_ENSOANP00000016591             ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000059619          ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000029448           ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000027009             ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000021890             ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000034022            ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000034020            ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000027821               ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000021904           ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000034033            ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000021744              ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000000956            ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000009993           ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000027015             ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000004372             ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000047678          ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000364878                 ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000012901              ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000017024           ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000001569               ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000006490            ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000013201            ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000034228                ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000013361         ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000035020             ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000059407                ------------------------------------------------------------------------------------------------------------------------
O_latipes_ENSORLP00000007938              ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000019853             ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000013027             ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000068268                ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000008601                ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000015203           ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000029853               ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000006831         ------------------------------------------------------------------------------------------------------------------------
T_guttata_ENSTGUP00000013612              ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000003321             ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000031895             ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000022672           ------------------------------------------------------------------------------------------------------------------------
C_elegans_C48D1.2                         ------------------------------------------------------------------------------------------------------------------------
O_latipes_ENSORLP00000015114              ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000005409           ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000016588              ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000312664                 ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000033921          ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000024166               ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000037606             ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000083664                ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000013740            ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000020323             ------------------------------------------------------------------------------------------------------------------------
O_anatinus_ENSOANP00000005545             ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000001598            ------------------------------------------------------------------------------------------------------------------------
T_guttata_ENSTGUP00000017449              ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000028116               ------------------------------------------------------------------------------------------------------------------------
O_latipes_ENSORLP00000010095              ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000003205               ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000010379             ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000010874         ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000023821           ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000035938           ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024809            ------------------------------------------------------------------------------------------------------------------------
O_anatinus_ENSOANP00000015596             ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000019797             ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000017020             ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000054330          ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000311032                 ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000009934         ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024812            ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024816            ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000075318                ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000063081                ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000017288               ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000007986         ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000015808              ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000022078         ------------------------------------------------------------------------------------------------------------------------
O_anatinus_ENSOANP00000000517             ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000040691             ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000002670         ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000019984                MD----------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000014096           ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000002083               ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000002346            ------------------------------------------------------------------------------------------------------------------------
D_melanogaster_FBpp0084848                ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000091238             ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000221740                 ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000023986           ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000031759             ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000008661            ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000009923         ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP011951-PA                   ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000024183              ------------------------------------------------------------------------------------------------------------------------
O_latipes_ENSORLP00000010793              ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000024485         -------------------EFRLLLHQICEGLTGENVSMMKFLCKDAIP--RSRELETALDFMEYFEAKGWIQEGDLGFLAEVLYRINRHDLLKLLPGVKNRRDYEENFQAQQNNFTTYR
A_carolinensis_ENSACAP00000013788         ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000005560            ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000032189           ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000002956         ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000037898              ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000004412            ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000009643           ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000012869               ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000022652             ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000021186         ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000002138             ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000056642          ------------------------------------------------------------------------------------------------------------------------
A_aegypti_AAEL003444-PA                   ------------------------------------------------------------------------------------------------------------------------
T_guttata_ENSTGUP00000006879              ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000022402            ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000014503               ------------------------------------------------------------------------------------------------------------------------
T_guttata_ENSTGUP00000004278              ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000075650                ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000019870               ------------------------------------------------------------------------------------------------------------------------
T_guttata_ENSTGUP00000011206              ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000026062             ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000011493         ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000286186                 -MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFR---
R_norvegicus_ENSRNOP00000017972           ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000048878          -MKSQGQHWCSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVP-KKLEKSSSASDVFEHLLAEDLLSEDDPFFLAELLYIIRQKKLLQHLNYTKEEVERLLPTRQRVSLFR---
M_mulatta_ENSMMUP00000040583              ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000036247            ------------------MDFHTFLYGIAEEIDSADLASLKFLCLDQIPLKKQQHIKDALVLFQTLEERGLLEEDNLFFLKELLFRINRIDLLNEPLNTKGPEMERELQVPNKARISPYR
X_tropicalis_ENSXETP00000052017           ------------------------------------------------------------------------------------------------------------------------
G_gorilla_ENSGGOP00000011776              ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000365051                 ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000072390                ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000006831                ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000013731             ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000005556            ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000030747             ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000018104            ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000044662             ----------------CNMDFQARLLKVGNDLRKDEVRALVFLCSDILGC-NPAAVQSAGDLFSRLSDQDHLSEEQPHLLVELLGIIQRTKLLRDHNLPRTGAQDLISPYSCKSR-----
A_gambiae_AGAP000830-PA                   ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000013506               LKSFKPHWISSNMEDDDSLQFRQLLLLIDEGLGAEDVAALKFLCTDLIPFRKLESVQSAMDIFQLLIDEDYLNEEDTFLLAELLYRIKYHSLLSKLGYTKEKVQECLHEKGKVSPYR---
B_taurus_ENSBTAP00000008706               ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000005216          ------------------------------------------------------------------------------------------------------------------------

                                                  130       140       150       160       170       180       190       200       210       220       230       240
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000376849                 GKKKRRKNFEAMFKGILQSGLDNFVINHMLKNNVAGQTSIQTLVPNTDQKSTSVKKDNHKKKTVKMLEYLGKDVLHG--VFNYLAKHD-VLTL-------KEEEKKKYY-DTKIEDKALI
P_troglodytes_ENSPTRP00000007279          GKKKRRKNFEAMFKGILQSGLDNLVINHMLKNNVAGQTSIQTLVPNTDQKSTSVKKDNHKKKTVKMLEYLGKDVLHG--VFNYLAKHD-VLTL-------KEEEKKKYY-DAKIEDKALI
P_pygmaeus_ENSPPYP00000004374             CKKKRRKNFEAVFKCILQSGLDNLVINHMLKNNVAGQTSIQTL-PNTDQKSTSVKKDNHKKKTIKMLEYLGKDVLHG--VFNHLAKHD-VVTL-------KEEEKKKYY-NAKIEDKALI
G_gorilla_ENSGGOP00000015374              --------------------------------------------------------DNHKKKTVKMLEYLGKDVLHG--VFNYLAKHD-VLTL-------KEEEKKKYY-DAKIEDKALI
M_mulatta_ENSMMUP00000012894              -------------------------------------------------------------------------MLHG--VFNHLAKHD-VLTL-------NEEEKENYY-NVKIEDKALI
P_troglodytes_ENSPTRP00000041705          -----------------------------------------------------MAEGNHRKKPLKMLESLGKDFLTG--VLDNLVEQN-VLNW-------KEEEKKKYY-DAKTEDKVRV
P_pygmaeus_ENSPPYP00000004373             -----------------------------------------------------MAEGNHRKKPLKMLESLGKDFLTG--VLDNLVEQN-VLNW-------KEEEKKKYY-DAKTEDKVRV
H_sapiens_ENSP00000347741                 -----------------------------------------------------MAEGNHRKKPLKVLESLGKDFLTG--VLDNLVEQN-VLNW-------KEEEKKKYY-DAKTEDKVRV
B_taurus_ENSBTAP00000027820               -----------------------------------------------------MAEDKHNKNPLKMLESLGKELISG--LLDDFVEKN-VLKL-------EEEEKKKIY-DAKLQDKARV
M_mulatta_ENSMMUP00000012893              ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000031565           --------------MYSSRQQHGLSLEHILKNGEIARDGKTYVVPIVEGVFVFLTEDKHDKNPFKILETVGKELITG--VLHGLLEKD-ILKL-------EDAEKKTFY-DAKPEDKPWV
E_caballus_ENSECAP00000010831             -----------------------------------------------------MAEDRQERNLLKTLESVGKELITG--LSVGLVEKD-VLKL-------KEEERKKFY-EAKPGDKPWV
M_musculus_ENSMUSP00000027012             -----------------------------------------------------MAENKHPDKPLKVLEQLGKEVLTE--YLEKLVQSN-VLKL-------KEEDKQKFN-NAERSDKRWV
R_norvegicus_ENSRNOP00000058685           -----------------------------------------------------LTENNHPDKPLKVLEELGKEFLTE--YLEKLVQSN-VLKL-------KEEEKQKFN-NAERSDKRWV
P_pygmaeus_ENSPPYP00000004377             -----------------------------------------------------MADKVLKEKRKLFIRSMGEGTING--LLDELLQTR-VLNK-------EETEKVKRE-NATVMDKTRA
H_sapiens_ENSP00000260309                 -----------------------------------------------------MADKVLKEKRKLFIRSMGEGTING--LLDELLQTR-VLNK-------EEMEKVKRE-NATVMDKTRA
E_caballus_ENSECAP00000006810             ----------------------------------------------------LAGRGPEKEDPVNLMKSIARNMFEG--FLDDL-ENN-VLSR-------DDLRKLGKR-VNRIVNGTEN
O_anatinus_ENSOANP00000016591             -----------------------------------------------------PPAQLLKDRWCLIIESLTHGMISG--LLDDLLQMQ-VINQ-------EEMDTVREE-HHRPAEKTRA
P_troglodytes_ENSPTRP00000059619          -----------------------------------------------------MADKFLKEKRKLFIRSMGEGTING--LLDELLQTR-VLNQ-------EEMEKVKRE-NATAMDKTRA
R_norvegicus_ENSRNOP00000029448           ----------------------------------------------------FTAKRTHERDPIYKIKGLAKDMLDG--VFDDLMDKN-VLNG-------DELLKIGEG-ASLILSKAEN
M_musculus_ENSMUSP00000027009             ----------------------------------------------------MAARRTHERDPIYKIKGLAKDMLDG--VFDDLVEKN-VLNG-------DELLKIGES-ASFILNKAEN
E_caballus_ENSECAP00000021890             ------------------------------------------------------TGNVLKEKRRLFIRSVGTGTVNS--LLDELLEKR-VLNQ-------EEMEKVRDE-NATVMDKARA
M_domestica_ENSMODP00000034022            -----------------------------------------------------LTDKVLMEKRRLFVESVDRGVMNG--LLDDLLEVQ-VLNL-------EEMEIVREE-SKTNRDKARV
M_domestica_ENSMODP00000034020            ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000027821               ------------------------------------------------------------EKRKLFVHSVSKGTING--LLDELLEKR-VLNQ-------EEMEKIRDE-NDTAMDRARV
C_familiaris_ENSCAFP00000021904           ----------------------------------------------------VLTGKRQSQDPVNAIKVVASTMLNS--FLEDLKEKN-VLNK-------QELQTMGQT-VNVITKKTEN
M_domestica_ENSMODP00000034033            -----------------------------------------------------LTDKVLKEKRRLFVESVDRGVING--LLDDLLELQ-VLNL-------EEMEILKEE-SRTIRDKARV
M_mulatta_ENSMMUP00000021744              ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000000956            -----------------------------------------------------MADRILKDRRKRFINSVGTGTING--LLDELLEKR-VLNQ-------EEMEKVRVE-NATVMDKARA
R_norvegicus_ENSRNOP00000009993           -----------------------------------------------------MADKILRAKRKQFINSVSVGTING--LLDELLEKR-VLNQ-------EEMDTIKLA-NITVMEKARD
M_musculus_ENSMUSP00000027015             -----------------------------------------------------MADKILRAKRKQFINSVSIGTING--LLDELLEKR-VLNQ-------EEMDKIKLA-NITAMDKARD
P_pygmaeus_ENSPPYP00000004372             ----------------------------------------------------FTDEKPSNGVPVHMVKLLIRTFLDG--IFDDLMENN-VLNT-------DEIHLIGTC-LKFVVSNAEN
P_troglodytes_ENSPTRP00000047678          ----------------------------------------------------MADEKPSNGVLVHMVKLLIKTFLDG--IFDDLMENN-VLNT-------DEIHLIGKC-LKFVVSNAEN
H_sapiens_ENSP00000364878                 ----------------------------------------------------MADEKPSNGVLVHMVKLLIKTFLDG--IFDDLMENN-VLNT-------DEIHLIGKC-LKFVVSNAEN
M_mulatta_ENSMMUP00000012901              ------------------------------------------------------TDKVLKEKRKLFIHSMGEASL---------------------------------------------
X_tropicalis_ENSXETP00000017024           ------------------------------------------------------LAAQLKKVRKLFIDGCNAAIINN--LLDDLLDKS-VLTD-------SEVEYINEC-NAITKDRCRR
G_gallus_ENSGALP00000001569               ----------------------------------------------------------LLRVRADFVSRVRKAVVSN--LLDELLAHR-VLNQ-------AEVDEVQEG-NPVTTDKARS
O_cuniculus_ENSOCUP00000006490            -----------------------------------------------------------YKDVLKEMESAGKAIAGS--FMDNLVKKK-VIKL-------EKAKREKFY-DAKTHKKAQI
G_aculeatus_ENSGACP00000013201            -----------------------------------------------------YFSDKLKKVRTKFVEKASMSLIKQ--LLDDLLDNG-ILND-------GQKDSILEE-NGTKADRARN
D_rerio_ENSDARP00000034228                ----------------------------------------------------------MAKSIKDHLQDALSNIGAD--NLRRFQSR--LGDR-------KQEPRVRKSTIEKLKDEIDL
A_carolinensis_ENSACAP00000013361         ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000035020             -----------------------------------------------------ME-DKLTSIRLMFVEKVSTQMINQ--LLDDIFMDG-IVSE-------MEKESITEE-SNIRSDKARR
D_rerio_ENSDARP00000059407                ----------------------------------------------------------KMEDITKLITDVLEELVES--ELKEFKRQLWMGVK-------KGVEAIPRG-KLENKDRQDV
O_latipes_ENSORLP00000007938              ----------------------------------------------------------------------------------MLLQDK-VLND-------EERESICEE--KSRADMARS
T_rubripes_ENSTRUP00000019853             -----------------------------------------------------LP-DQLASIRPMFVEKVSTQMINQ--LLDDIFMDG-IVSE-------MEKESITEE-SNIRSDKARR
T_rubripes_ENSTRUP00000013027             -----------------------------------------------------MAICQLDSIRLMFVEKVSTQMINQ--LLDDIFMDG-IVSE-------MEKESITEE-SNIRSDKARR
D_rerio_ENSDARP00000068268                -----------------------------------------------------------MEDITQLLSDVLEDLVES--ELKQFTRQLWIGVK-------PGVEPIPRG-KLENKDRQDV
D_rerio_ENSDARP00000008601                ------------------------------------MTEEVNWDEDLEVDAVVQNLNLYKTVMRNDKNSNSEVQLSN--ELVDFAVELTCGHR-------MPVDYVVAWFKCYLKQKETD
X_tropicalis_ENSXETP00000015203           -------------------------------------------------MLGGMQKHHKDALQRLRVTLLHDMIIEE--LVEHLVSSG-ILTP-------IMHSTIMAH--RSEYKQNVT
G_gallus_ENSGALP00000029853               -------------------------------------------------GACGMQRYHQEALKKNRVMLARELVLKE--LMEHMIEKD-IITI-------EMVEMIQAK--SGSFSQNVE
A_carolinensis_ENSACAP00000006831         ---------------------------------------------SRMLGVCGMQKCHQEALKKNRVSLAKQLVLKE--LMEHLIEKD-VITE-------EMMEMIQAK--AGNFSQNIE
T_guttata_ENSTGUP00000013612              -----------------------------------------------MLAACGMQRCHQEALKKNRVMLAKQLVLNV--LVEHMVEKD-IIPT-------EMVEMIQAK--SGSFDRNVE
E_caballus_ENSECAP00000003321             ----------------------MAAPSAPSLPALQQKGLMAADRGRRILGVCGMHPDHQEALKKNRVVLAKQLLLSE--LLEHLLEKD-IITL-------EMRELIQAK--VTSFGQNVE
M_musculus_ENSMUSP00000031895             ----------------------MAAPSGRSQSSLHRKGLMAADRRSRILAVCGMHPDHQETLKKNRVVLAKQLLLSE--LLEHLLEKD-IITL-------EMRELIQAK--GGSFSQNVE
R_norvegicus_ENSRNOP00000022672           ----------------------MAASSGRSQSSLHRKGLMAADRRSRILAVCGMHPDHQETLKKNRVVLAKQLLLSE--LLEHLLEKD-IITL-------EMRELIQAK--GGSFSQNVE
C_elegans_C48D1.2                         ----------------------------------------------------MMRQDRRSLLERNIMMFSSHLKVDE--ILEVLIAKQ-VLNS-------DNGDMINSC--GTVREKRRE
O_latipes_ENSORLP00000015114              ---------------------------------------------RSVTQKCGMQKRDAEALRNCSVCLLKDLVVDE--LLIQALVKDGILTQ-------NMAESIMVQ--KTSHHRSFK
C_familiaris_ENSCAFP00000005409           ----------------------MAAASAGRPAALQRKAPTAAGRGRRILGVCGMHPDHQEALKKNRVVLAKQLLLSE--LLEHLLEKD-IITL-------EMREHIQAK--VGGFSQNVE
M_mulatta_ENSMMUP00000016588              ----------------------------------------------RILGVCGMHPHHQETLKKNRVMLAKQLLLSE--LLEHLLEKD-IITL-------EMRELIQAK--VGSFSQNVE
H_sapiens_ENSP00000312664                 ----------------------MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSE--LLEHLLEKD-IITL-------EMRELIQAK--VGSFSQNVE
P_troglodytes_ENSPTRP00000033921          ----------------------MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSE--LLEHLLEKD-IITL-------EMRELIQAK--VGSFSQNVE
B_taurus_ENSBTAP00000024166               ----------------------MAAPSAGFQYPLQPKEQMAADRGRRMLRGCGMHPDHQEALKKNRVVLAKELLLSE--LLEHLLEKD-IITL-------EMREHIQAK--TGSFGQNVE
T_rubripes_ENSTRUP00000037606             ---------------------------------------------RSKMLHCGMREQDARTLRRQSAVLCKQLVVDE--LLIQCLQADDILTE-------SMAESIMAE--QTSQKRSWR
D_rerio_ENSDARP00000083664                -----------------------------------------------MLGECGMTKWERLALRRNSVKMLQDLVVDD--LLIQCLQQDGILTD-------SMAESIMAK--PTSQGRSHQ
G_aculeatus_ENSGACP00000013740            ---------------------------------------------------CGMQERDRLALRTRSTVLCKQLVVDE--LLIQSLQTDEILTE-------AMAENIMAE--QTSQKRSWR
P_pygmaeus_ENSPPYP00000020323             ----------------------MAAPTAGSWSTFEHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSE--LLEHLLEKD-IITL-------EMRELIQAK--VGSFSQNVE
O_anatinus_ENSOANP00000005545             -----------------------------------------------------MQPCHQEALKKNRVALAKQLMLSE--LLEHLLEKD-VITM-------EMRELIQAK--AGSFSQNVE
M_domestica_ENSMODP00000001598            ----------------------------------------------RMLGVWGMEQEHQEALKKNRVVLAKQLLLSE--LLEHLLEKD-IITL-------EMRELIQAK--VGSFSQNVE
T_guttata_ENSTGUP00000017449              -----------------------------------------------------MEERQRRALRRGRARLVAALRVEP--LWEPLEQRG-LFTR-------PMLEELQSA--GSRGEQARQ
B_taurus_ENSBTAP00000028116               ------------------------------------------------------------------------------------------ESK-------EMSSP---------------
O_latipes_ENSORLP00000010095              -------------------------------------------------------------------------------------MASNRPGE-------DSTDARK-------------
B_taurus_ENSBTAP00000003205               -----------------------------------------------------MNEADRLLLRRYRVRLVGELQVAS--LWDALLSRE-LFTP-------DMIEDIQRAGSGSRRDQARQ
E_caballus_ENSECAP00000010379             ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000010874         ------------------------------------------------MLQCGMVERDAQALKKQSAVLFKQLVVDE--LLIQFLQADDILTD-------SMAESILAE--QTSHKRCWK
C_familiaris_ENSCAFP00000023821           -----------------------------------------------------------------------------------------MVDS-------EIRQA---------------
X_tropicalis_ENSXETP00000035938           ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024809            ------------------------------------------------------------------------------------------------------------------------
O_anatinus_ENSOANP00000015596             --------------------------------------------------------------------------------------------------------------AGTRRDQARQ
E_caballus_ENSECAP00000019797             ---------------------------------------------------------------------------------------M-ENSK-------ISVDSKS-------------
P_pygmaeus_ENSPPYP00000017020             ---------------------------------------------------------------------------------------M-ENTE-------NSVDSKS-------------
P_troglodytes_ENSPTRP00000054330          ---------------------------------------------------------------------------------------M-ENTE-------NSVDSKS-------------
H_sapiens_ENSP00000311032                 ---------------------------------------------------------------------------------------M-ENTE-------NSVDSKS-------------
T_nigroviridis_ENSTNIP00000009934         ----------------------------------------------------------------------------------MSANGP-ASGE-------DFTDASKG------------
G_aculeatus_ENSGACP00000024812            ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024816            ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000075318                -----------------------------------------------------MADQLLENLRPDLIKGLSERVING--LLDDLQQKK-VFGE-------EEIEDIQHR-MKTRADQARH
D_rerio_ENSDARP00000063081                ----------------------------------------------------MSKKESTQRILQHKVFLIDTLSVEASFILQNVQQAK-LITQ-------RDYNNLSDV--SERETKIIK
G_gallus_ENSGALP00000017288               -------------------------------------------------------------------------------MMTDIKDGP-RSGE-------DVSDARS-------------
C_intestinalis_ENSCINP00000007986         -----------------------------------------------------MLSTHKEKLRTNRHTLCKELVVDE--LLQELIGEG-IFND-------ILADRVLSH--QRDFKKNVE
M_mulatta_ENSMMUP00000015808              ---------------------------------------------------------------------------------------M-ENTE-------NSVDSKS-------------
T_nigroviridis_ENSTNIP00000022078         --------------------------------------------------------------------MAGEAAGIP--ELGGEAEGE-HRCE-------DDVDAKPD------------
O_anatinus_ENSOANP00000000517             ---------------------------------------------------------------------------------------A-ASGE-------VMVDSKS-------------
T_rubripes_ENSTRUP00000040691             --------------------------------------------------------------------------------TNMSANGP-SPGG-------DFTDAKKGA-----------
A_carolinensis_ENSACAP00000002670         ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000019984                -------------------------------KEALTSENEVSGDDQENYGKGDVTDAKPDPKAMCRVDKE-ALTSEI--EVLEEDQDS-YGEE-------DVTDAKPD------------
R_norvegicus_ENSRNOP00000014096           ---------------------------------------------------------------------------------------M-DNNE-------TSVDSKS-------------
G_gallus_ENSGALP00000002083               -----------------------------------------------------MEEAQRSALRRGRVRLVEGLRPEV--LWGPLQARG-VFTS-------AMVEDMQST--GTRREQARQ
O_cuniculus_ENSOCUP00000002346            ------------------------------------------------------------------------------------------------------------------------
D_melanogaster_FBpp0084848                -----------------------------------------------------------------MDATNNGESADQ--VGIRVGNPE--QPN-------DHTDALGSVGSGGAGSSGLV
M_musculus_ENSMUSP00000091238             ---------------------------------------------------------------------------------------M-ENNK-------TSVDSKS-------------
H_sapiens_ENSP00000221740                 -----------------------------------------------------------------------------------------------------MSNP---------------
C_familiaris_ENSCAFP00000023986           -----------------------------------------------------MDEAERRALRRCRVRLVRELQVAA--LWDALLSRE-LFTA-------AMVEDLQHAGSGSRSDQARQ
T_rubripes_ENSTRUP00000031759             -----------------------------------------------------------------SMQMAGEPTEIS--DLGGEVEEG-GQSE-------DDVDAKPD------------
G_aculeatus_ENSGACP00000008661            -----------------------------------------------------------------QVNGA-RLTSAQ--DVA--AEEG-GPTG-------DQTDAKPD------------
A_carolinensis_ENSACAP00000009923         ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP011951-PA                   ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000024183              -----------------------------------------------------------------------------------------------------MSNL---------------
O_latipes_ENSORLP00000010793              --------------------------------------------------------------------------------MDMAETAEELSGK-------DQVDTKP-------------
C_intestinalis_ENSCINP00000024485         ------------------------------------VVCFMLADELTEGDLKILKRLCAGKMSKANVR--RSVDVLS--WLTCMEEED-LLSE-------GDLDFIMSILQHLDNQKPYK
A_carolinensis_ENSACAP00000013788         ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000005560            ---------------------------------------------------------------------------------------M-EDTG-------TTVDAKS-------------
C_familiaris_ENSCAFP00000032189           ---------------------------------------------------------MGEQRNTSSKELAAAEATGQ--SGKELEVSM-ENTE-------NSVDAKS-------------
C_intestinalis_ENSCINP00000002956         ----------------------------------------------------AMKKRHRNTLIKNRVKLAKCLHLDE--VLQYLVQCG-ILTD-------VTVERITSK--PTRFSQNVA
M_mulatta_ENSMMUP00000037898              ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000004412            -----------------------------------------------------MEESQRELFQKNRLRLVCELQVEP--LWDLMLDRE-LFTR-------DMIEDIQRA--GTRRDQARQ
R_norvegicus_ENSRNOP00000009643           ------------------------------------------------------------------------------------------MDS-------ETINP---------------
B_taurus_ENSBTAP00000012869               -------------------------------------------------MEGSLGSGRRSGSDGQPAPPKISPTTEE--LQSRLQETLDLLSS-------QELRSFRDHLKKVEPPVSQV
T_rubripes_ENSTRUP00000022652             -------------------------------------------------------------------------------------GSDAELGK-------TATDSS--------------
T_nigroviridis_ENSTNIP00000021186         ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000002138             -----------------------------------------------------MDEADRRLLWRCRLRLVEELQVDQ--LWDALLSRE-LFRP-------HMIEDIQRAGSGSRRDQARQ
P_troglodytes_ENSPTRP00000056642          ------------------RGGRPWGGGGSWGLGRAAEARKRTEAAWSLSWLLAMDEADRRLLRRCRLRLVEELQVDQ--LWDALLSRE-LFRP-------HMIEDIQRAGSGSRRDQARQ
A_aegypti_AAEL003444-PA                   -----------------------------------------------------------------------------------------MDTT-------DELDV---------------
T_guttata_ENSTGUP00000006879              --------------------------------------------------------------------------------MTDIGDGA-HLGK-------DLADTKS-------------
G_aculeatus_ENSGACP00000022402            -------------------------------------------------------------------------------------MSVNGPGE-------DRTDAKT-------------
G_gallus_ENSGALP00000014503               ------------------------------------------------------------------------------------------------------------------------
T_guttata_ENSTGUP00000004278              ---------------------------------------------------------------------------------MSGSERRPPAGH-------VQLDSRP-------------
D_rerio_ENSDARP00000075650                ----------------------------------------------------MDKKESVDKICENKIFLLETLSVDANFILQHVQQAK-LITL-------RDYNNLSDF--PQRETKIIN
G_gallus_ENSGALP00000019870               ---------------------------------------------------------------------------------MSGAERRPAAGR-------VQLDSKPT------------
T_guttata_ENSTGUP00000011206              ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000026062             -----------------------------------------------------------------------MTDDQD--CAAELEKVD-SSSE-------DGVDAKPD------------
C_intestinalis_ENSCINP00000011493         -------------------------------------------MDPHPADFPEPPPQPRITLRSDTVDSSVFHDDDNLFSMDDAVEQPDSFDAVPPNSYPSPNSSLSTSYSGGDILSMAS
H_sapiens_ENSP00000286186                 ------------------------------------NLLYELSEGIDSENLKDMIFLLKDSLPKTEMTSL---------SFLAFLEKQGKIDE-------DNLTCLEDLCKTVVPKLLRN
R_norvegicus_ENSRNOP00000017972           -----------------------------------------------------MEEADRQLLRRCRVRLVRELQVAE--LWDALLSRE-LFTR-------DMIEDIQRAGSGSRRDQARQ
P_troglodytes_ENSPTRP00000048878          ------------------------------------NLLYELSEGIDSENLKDMIFLLKDSLPKTEMTSL---------SFLAFLEKQGKIDE-------DNLTCLEDLCTTVVPKLLRN
M_mulatta_ENSMMUP00000040583              -----------------------------------------------------MDEADRRLLRRCRLRLVEELQVDQ--LWDALLSRE-LFKP-------HMIEDIQRAGSGSRRDQARQ
M_domestica_ENSMODP00000036247            LHLHTTIWPFRDNWTCRITLSVSFTSRTKQLLSVMVILLFNLSEGVGPSELKSIKFMLSSKIPKCKIE--DDMTLMD--LFIEMEKRG-ILGE-------GNLDALKIVCDQIDKSLLKK
X_tropicalis_ENSXETP00000052017           -------------------------------------------------------------------------------MASAKQQSSPSAGQ-------IEKDSSS-------------
G_gorilla_ENSGGOP00000011776              ----------------------------------------------------MADEKPSNGVPVHMVKLLIKTFLDG--IFDDLMENN-VLNT-------DEIHLIGKC-LKFVLSNAEN
H_sapiens_ENSP00000365051                 ------------------RGGRPWGGGGSWGLGRAAEARKRTEAAWSLSWLLAMDEADRRLLRRCRLRLVEELQVDQ--LWDALLSRE-LFRP-------HMIEDIQRAGSGSRRDQARQ
D_rerio_ENSDARP00000072390                ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000006831                ------------------------------------------------------------------------------------------MNG-------DCVDAKRVDTT---------
E_caballus_ENSECAP00000013731             -----------------------------------------------------------------------MADDQD--CVVEQGAGD-STST-------DAVDAKPD------------
M_domestica_ENSMODP00000005556            ---------------------------------------------------------------------------------------M-EDTG-------TTVDAKS-------------
M_musculus_ENSMUSP00000030747             -----------------------------------------------------MDEADRQLLRRCRVRLVSELQVAE--LWDALLSRE-LFTR-------DMIEDIQQAGSGSRRDQARQ
M_domestica_ENSMODP00000018104            ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000044662             ------------------------------------KLLYSLSEELTADDLKDIKFLLNNKLPRGKLEEVTTLE-----VFMELEHRA-LISD-------TDLGFLESIIQPVCPVLLEK
A_gambiae_AGAP000830-PA                   ---------------------------------------------------------MSMPDVVDIRNEINKEHVRE--SLDRNGDEQ-QLVQ-------DVNDALGT------------
G_gallus_ENSGALP00000013506               ------------------------------------QMLYELSENITNDMLQEIVFLLRNHLPKRRRTISAL-------ELLILLEKQCLLTE-------NNVQILEEVFRNVSPDLLET
B_taurus_ENSBTAP00000008706               ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000005216          --------------------------------------MDCVGWPPGRKWHLEKNTSCGGSSGICASYVTQMADDQG--CIEEQGVED-SANE-------DSVDAKPD------------

                                                  250       260       270       280       290       300       310       320       330       340       350       360
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000376849                 ------LVDSLR-KN-----RVAHQMFTQTLL--NMDQKITSVKPLLQIEAGP-------------------------------------------------------------------
P_troglodytes_ENSPTRP00000007279          ------LVDSLR-KN-----RVAHQMFTQTLL--NMDQKITSVKPLLQIEAGP-------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000004374             ------LVDSVR-KN-----RVAHQIFIQTLL--DMDQKITSVKPLLQIEAGP-------------------------------------------------------------------
G_gorilla_ENSGGOP00000015374              ------LVDSXR-KK-----RVAHQMFTQTLL--NMDQKITSVKPLLQIEAGP-------------------------------------------------------------------
M_mulatta_ENSMMUP00000012894              ------LVDSVR-KN-----RVAHQRFTQTLL--NMDQRITSVKSLLQIEAGP-------------------------------------------------------------------
P_troglodytes_ENSPTRP00000041705          ------MADSIQEKQ-----RMAGQMLLQTFF--NIDQISPNKKAHPNMEAGP-------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000004373             ------MADSIQEKQ-----RMAGQMLLQTFF--NIDQISPNKKAHPNMEAGP-------------------------------------------------------------------
H_sapiens_ENSP00000347741                 ------MADSMQEKQ-----RMAGQMLLQTFF--NIDQISPNKKAHPNMEAGP-------------------------------------------------------------------
B_taurus_ENSBTAP00000027820               ------LVDSIRQKN-----QEAGQVFVQTFL--NIDKNSTSIKAPEETVAGP-------------------------------------------------------------------
M_mulatta_ENSMMUP00000012893              ------MADSIQEKQ-----RMAGQMLLQTFF--NIDQISPSKKAHLNMEARP-------------------------------------------------------------------
C_familiaris_ENSCAFP00000031565           ------ILNSVRQKR-----QEAGQALVHTFI--NTDKYSTSVEAFVENMPGPTI-----------------------------------------------------------------
E_caballus_ENSECAP00000010831             ------LVDSVRDRR-----HEAGQILWQALF--NIDRSVISRKALEEIAAGP-------------------------------------------------------------------
M_musculus_ENSMUSP00000027012             ------FVDAMKKKH-----SKVGEMLLQTFF--SVDPGSHHGEANLEM-----------------------------------------------------------------------
R_norvegicus_ENSRNOP00000058685           ------FVDVLKRKH-----NQVGKMLLQTFL--NVDSGSHHGEANLEM-----------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000004377             ------LLDSLIPKG-----ARACEICITYIC--EEDSYLAETLGLSADQTSGNYLN------------MQDSQGVLSSFPAPQAVQDNPAM----------------------------
H_sapiens_ENSP00000260309                 ------LIDSVIPKG-----AQACQICITYIC--EEDSYLAGTLGLSADQTSGNYLN------------MQDSQGVLSSFPAPQAVQDNPAM----------------------------
E_caballus_ENSECAP00000006810             ------LVEDLSEKT-----EVAGKIFLKHLL--KPKKQMNL-KSLADYEDDESEDTESPFSSTESACEGEDEETEENAGLSQASVPP-----MTDPQE---------------------
O_anatinus_ENSOANP00000016591             ------LLNSVIPKG-----DLASQIFIDSLC--KKNPFVAAKLGLSAGGQGQSGNT-------QFVGQSQMIPAVATSCSVPQALQAPKTLTE--------------------------
P_troglodytes_ENSPTRP00000059619          ------LIDSVIPKG-----AQACQICITYIC--EEDNYLAGTLGLSADQTSGNYLN------------MQDSQGVLSSFPAPQAVQDNPAM----------------------------
R_norvegicus_ENSRNOP00000029448           ------LVESFFEKT-----EMAGKIFAGHIA--NSDKQLSLLQADRNQITGPSFQILVFNSLSESRGKVEDEEMEVNVGVAHASHLM-----LTVPQG---------------------
M_musculus_ENSMUSP00000027009             ------LVENFLEKT-----DMAGKIFAGHIA--NSQEQLSL-QFSNDEDDGPQ-KICTPSSPSESKRKVEDDEMEVNAGLAHESHLM-----LTAPHG---------------------
E_caballus_ENSECAP00000021890             ------LIDAVIRKG-----PQACQIFIGHIC--EDDPHLAETLRLSSGPQSGNFLK------------TQDSQAVVHSSPALQAMPDDLAK----------------------------
M_domestica_ENSMODP00000034022            ------LIDAVISKG-----PKASQCFTKSIC--ERDGHLAEKLGLSSELNSNQS---------HISLCREQAPRPINICILRNDNIERT------------------------------
M_domestica_ENSMODP00000034020            ------LIAS--------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000027821               ------LIDTVIRKG-----PQACQICISHIC--EEDSHLAGILGLTSGSQSENYLR-------------QKPQAVVPPFPAPQAMLDNPVK----------------------------
C_familiaris_ENSCAFP00000021904           ------LVGDLTEKT-----QVVGKIFKDHFL--NSGSLLSLSWSSTSATKPSGSCRPSYLTQARSRKKEEVPKILVFVIFLYKMVFLLQVLQ---------------------------
M_domestica_ENSMODP00000034033            ------LIDAIISKG-----PKASQCFTKSIW--ERDGHLAEKLGLSSGKRK------------YLLGKADHSIHGEKLKTKQRHTIGKWK-----------------------------
M_mulatta_ENSMMUP00000021744              ---------------------------------------------------------------------------------------------LSAPLE---------------------
O_cuniculus_ENSOCUP00000000956            ------LLDCVIRKG-----PQACQICINHIC--EDDCHLAGLLGLSSGPQSENHFN------------AQDSLEAFSSFSAPQTTQDNQVV----------------------------
R_norvegicus_ENSRNOP00000009993           ------LCDHVTKKG-----PRASQMFITYIC--NEDCYLAEILELQSGPSAETVFV------------TEDSKG-GHPFSSETKEKLNKEG----------------------------
M_musculus_ENSMUSP00000027015             ------LCDHVSKKG-----PQASQIFITYIC--NEDCYLAGILELQSAPSAETFVA------------TEDSKG-GHPSSSETKEEQNKED----------------------------
P_pygmaeus_ENSPPYP00000004372             ------LVDDITQTA-----QIAGKIFREHLW--NSKKQLSS------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000047678          ------LVDDITETA-----QIAGKIFREHLW--NSKKQLSS------------------------------------------------------------------------------
H_sapiens_ENSP00000364878                 ------LVDDITETA-----QTAGKIFREHLW--NSKKQLSS------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000012901              ------------------------------------------------------------------------------------AMQDNPAM----------------------------
X_tropicalis_ENSXETP00000017024           ------MIDNIKNKG-----DYSSNILLQCLV--ENHKTLAKNMGLDVSEPAIA----------------------------PQPIQEQNKK----------------------------
G_gallus_ENSGALP00000001569               ------LIDTVRLKG-----PRASAIFIDSLR--KHDCNLAEQLRLCAHAEPPGAPLAAPSTVGFSDP----------------------------------------------------
O_cuniculus_ENSOCUP00000006490            ------LVDSLREKC-----HEEDQKLTETFL--NIDQNSTGMQXXXXXXXXX-------------------------------------------------------------------
G_aculeatus_ENSGACP00000013201            ------LIDVVKAKG-----NKASEILIASLE--SRDSSLFSELGLSSAQTAP-------------------------------------------------------------------
D_rerio_ENSDARP00000034228                ------VDLLVNTFT-----SDAVSVTVDILR--GIKCNAVAEELLENTGQVYSIFKLCKKNSHYTKPPIIITDVFMFCFLGGVSQPEPPVPEPIPK-----------------------
A_carolinensis_ENSACAP00000013361         ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000035020             ------LIDSVRKKG-----ERACKKMISHIQ--SRDPELSAVLGLSCGHPAPPVFNRRAPDGRSR-------VIFNSPINRCVLEGE--------------------------------
D_rerio_ENSDARP00000059407                ------VDYMVQHYS-----MDAGKIAVQALR--SIKQNERANRLESKLLEAVSS---------------------------SDLFQPQAQENEQNPEDPQSIN----------------
O_latipes_ENSORLP00000007938              ------LIDTVRKKG-----STASKMMINHFE--QKDPILFSELGLSCPEPAQTN-----------------------------------------------------------------
T_rubripes_ENSTRUP00000019853             ------LIDSVRKKG-----ERACKKMISHIQ--SRDPELSAVLGLSCGHPAPP--------GELRDDTLFQTDRIVSFRF-----QP--------------------------------
T_rubripes_ENSTRUP00000013027             ------LIDLVRKKG-----ERACKKMISHIQ--SRDPELSAVLGLSCGHPAPP--------GELR-------GQLESPAF-----ST--------------------------------
D_rerio_ENSDARP00000068268                ------VDSMVQQYS-----EDAGTITVQTLR--KIKQNERAKRLESNLLKV----------------------------------QSQGQENKQNSEEPQPIPQIISQPIQQIISQPIN
D_rerio_ENSDARP00000008601                FSCPHFIVDQGKTCG-----AKLSYQEICQLIPLSDKQREFLEENLAAIVARRLFDFKSCPGCQSHVERRNRNNLCVKCTICTANMTQTYYFCWKCRREWKGVTNNAECCGNTGC-----
X_tropicalis_ENSXETP00000015203           ------LLTQLPKRG-----PRAFSEFCNALH--ATGQRHLAEQLEEEAQQQQME-----------------SVTPEVHERSFPLPVQEST-----------------PSRPRRQFCR-E
G_gallus_ENSGALP00000029853               ------FLNLLPKRG-----PNAFSAFCEALQ--ETKQQHLAEMILKTESS--LR--------------HGIATLEQRYGSNLPLPLSESCNSK--------------RPRLIVFFCT-K
A_carolinensis_ENSACAP00000006831         ------FLNLLPKRG-----PKAFSAFCEALR--ETKQPHLEEMLLLNLIDFLLF----------------HHVIVPPQNAHLPL--HTVCDLL--------------PFAYQLFISSAE
T_guttata_ENSTGUP00000013612              ------FLNLLPKRG-----PNAFSAFCEALR--ETQQQHLETLILKTMSS--LS--------------QEIARLEHCHESDLPYPASESCNSK--------------RPRWL------E
E_caballus_ENSECAP00000003321             ------LLNLLPKRG-----PQAFEAFCVALR--ETKQGHLEDLLLTTLSG--LQ--------------HVLPPLSCDYDLSLPFPVCESC-----------------PPHKQLRLST-D
M_musculus_ENSMUSP00000031895             ------LLNLLPKRG-----PQAFDAFCEALR--ETRQGHLEDLLLTTLSD--IQ--------------HVLPPLSCDYDTSLPFSVCESC-----------------PPHKQLRLST-D
R_norvegicus_ENSRNOP00000022672           ------LLNLLPKRG-----PQAFDAFCEALR--ETRQGHLEDLLLTTLSD--IQ--------------HILPPLSCDYDSSLPFSVCESC-----------------PPHKQSRLST-D
C_elegans_C48D1.2                         ------IVKAVQRRG-----DVAFDAFYDALR--STGHEGLAEVLEPLARSVDSN---------------------------AVEFECPMSPASHRRSRALSPAGYTSPTRVHRDSVSSV
O_latipes_ENSORLP00000015114              ------LLLLLPKRG-----PRAFKSFCSALK--ETEQEHLCDLLTQ--EEEGRE--------VCLDTPLINSEEQSEVSSSMSYPIHDSE------------------GLQLEMRTNTE
C_familiaris_ENSCAFP00000005409           ------LLNLLPKRG-----PQAFDAFCVALR--ETKQGHLEDLLLTTLSG--LQ--------------HGLPPLSCDYDLSLTFPMCESC-----------------PPQKQLRLSP-D
M_mulatta_ENSMMUP00000016588              ------LLNLLPKR------PQAFDAFCEALR--ETKQGHLEDIELKLRVS--AL--------------MKPTGLGSDYNDILGLMVKLNT-----------------VFWFSV-YTT-D
H_sapiens_ENSP00000312664                 ------LLNLLPKRG-----PQAFDAFCEALR--ETKQGHLEDMLLTTLSG--LQ--------------HVLPPLSCDYDLSLPFPVCESC-----------------PLYKKLRLST-D
P_troglodytes_ENSPTRP00000033921          ------LLNLLPKRG-----PQAFDAFCEALR--ETKQGHLEDMLLTTLSG--LQ--------------HVLPPLSCDYDLSLPFPVCESC-----------------PLYKKLRLST-D
B_taurus_ENSBTAP00000024166               ------LLNLLPKRG-----PQAFDAFCVALR--ETKQSHLEELLLRTLSG--LQ--------------PVVPPLSCDYDLSLPFPVCESC-----------------TRHKRLHLSP-D
T_rubripes_ENSTRUP00000037606             ------LQLLLPKRG-----PKAFSSFCSALR--ATDQQHLCDLLTQTFETNGNG-----------------THVETCVDSSVPLPTQEAV------------------PGVCVCVCETE
D_rerio_ENSDARP00000083664                ------LLFLLPKRG-----PRAFSTFCSALK--ETEQHHLCKLLMDFTEKDKKN--------------------------SQYKLSPEIC------------------KKKNKHTHTHK
G_aculeatus_ENSGACP00000013740            ------LLLLLPKRG-----PRAFSSFCSALQ--ETEQQHLYELLIQSSEKDGKE-------------TPGMLMCGQFIDSSLPLPTQEVV------------------AAKRA-RTQAE
P_pygmaeus_ENSPPYP00000020323             ------LLNLLPKRG-----PQAFDAFCEALR--ETKQGHLEDMLLTTLSG--LQ--------------HVLPPLSCDYDLSLPFPVCESC-----------------PLYKKLRLST-D
O_anatinus_ENSOANP00000005545             ------FLNLLPKRG-----PKAFDAFCAALR--ETKQGHLQDLLYRTLSN--LSPPSTAVGALGTQGEELAGRLGGRWRGLPSLPSVSVCPVVVCPFLMVLGNSRLQPALSVGDLLP-E
M_domestica_ENSMODP00000001598            ------FLNLLPKRG-----PHAFEAFCDALR--ETKQGHLEDLLHRTLYS--FQ--------------NLRPPLGCDYDSSFPLPVCDSC-----------------PPHKQLRLSV-E
T_guttata_ENSTGUP00000017449              ------LIIDLETRG-----KQAFPAFLSILR--DTGQGHLAEMLMQECESRPVPPQLPDLRPVELEL------------------------QEANQRCAVVLQTA--------------
B_taurus_ENSBTAP00000028116               ------------------------------------------------------------------------------------------------------------------------
O_latipes_ENSORLP00000010095              ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000003205               ------LILDLETRG-----SQALPLFISCLE--DTGQDTLASLLKTSRQAAKQ-----------------------------------------SKPSQGKLAPVVLGPEELWPAKL--
E_caballus_ENSECAP00000010379             ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000010874         ------LLHLLPKRG-----PKAFSSFCSALR--ETDQKHLCDLLARTSQENGNG-----------------THLETCVDSSVPLPTQEAV--------------------PAKRARTQE
C_familiaris_ENSCAFP00000023821           ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000035938           ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024809            ------------------------------------------------------------------------------------------------------------------------
O_anatinus_ENSOANP00000015596             ------LVTDLETRG-----RRALSVFISCLR--ETDQHALAALLSEGCQAPQVTPV--DIRPVEIIRPGGQGDVCKYSKIHPKCYSPPLPFQSTSPLRGKEQWTGSVKPFV--------
E_caballus_ENSECAP00000019797             ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000017020             ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000054330          ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000311032                 ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000009934         ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024812            ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024816            ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000075318                ------VIDDVKRKG-----VKASEIMLASLK--TRDPHLYDTLGIERLL----------------------------------------------------------------------
D_rerio_ENSDARP00000063081                ------LLDKLIGRG-----EETCQEFIDLLR----------------------------------------------------------------------------------------
G_gallus_ENSGALP00000017288               ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000007986         ------FLTLLPGRG-----PNAFNAFRIALI--NSDQSHLAELLDPAQGVSQPNESNANDGSGGPELSASIFRFESIATANSNLPGTSGTSAPLSRRRPMENTDQSSTSIASSQVIYAN
M_mulatta_ENSMMUP00000015808              ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000022078         --------RRGRFL--------------