>D_rerio_ENSDARP00000090569
---------------MNV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------FARSSVLAAEMMDVFDRT-HTEKELVFQSKE
LCRDFIHSRITREGLSWSKVE-----------------------LDL-------------
-----------------------PEPRGVLVDVSVVLLKLGDELECMRPYVYRNIAKQLN
ISVSVE----AVVSDAFLSVATEVIAM--------------------DYATNTVFDFKG-
ITWGKVVAIYAVAAGLAVDCV-RLGHPVMVHTIVDSLGEFV-RRSLVPWLKKRGGW----
-----VDILK----------------CVVNMDSRA------HVHW-L------------S
TAVLTW-REFIKTM--------------------------YVYLTK--------------
----
>O_anatinus_ENSOANP00000008963
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEVMEVFDRS-PTDKELVSQAKA
LCREYIHSRLIRASLVWSKPD-----------------------YNV-------------
-----------------------PSPGGKLAEVSTILLRLGDELEYIRPNVYRNIARQLN
ISLHSE----TVVTDAFLAVATQIFSA-------------------------------G-
ITWGKVVSLYAVAAGLAVDCV-KQGQPAMVHTIVDCLGEFV-RKTLVTWLKRRGGW----
-----ADIMK----------------CVVNTDPSL------RSHW-L------------V
AAVCSF-GHFLKAI--------------------------FFVLLPER------------
----
>T_guttata_ENSTGUP00000006267
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEVMEVFDRS-PTDKELVSQAKA
LCRDYINSRLIQAGVSWSKPE-----------------------YNA-------------
-----------------------PVPGGKLAEVSTILLRLGDELEYIRPNVYRNIARQLN
ISLHSE----TVVSDAFLAVATQIFSA-------------------------------G-
ITWGKVVSLYAVAAGLAVDCV-RHAQPAMVHTIVDCLGEFV-RKTLVTWLKRRGGW----
-----ADITK----------------CVVNTDPNL------RSHW-L------------V
AAVCSF-GHFLKAI--------------------------FFVLLPER------------
----
>D_rerio_ENSDARP00000068408
---------------MEM------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEVMEVFDRS-PTDKELVSQSKV
LCRDYIHSRLHRAGIGWSKPE-----------------------HG--------------
-------------------------SGGTLAEVSSVLLWLGDELEYLRPNVYRNVARQLN
ITIASE----NIVSDAFLAVAAEIFST--------------------EYSRKGLEKHKG-
VTWGKIVSLYAVAGALAVDCV-RHGHPAMVHTIVDCMGEFV-RKSLASWLKKRGGW----
-----ADITK----------------CVVSTDPSF------HSHW-L------------V
TAACAC-GHYLKAV--------------------------VFYLLREK------------
----
>A_carolinensis_ENSACAP00000000851
---------------MDV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEVMEVFDRT-PTDKELVSQAKV
LCRDFIHSRLIRAGIGWNKPE-----------------------HSV-------------
-----------------------PVPGGKLAEVSNILLRLGDELEYIRPNLYRNVARQLN
ISLHSE----TVVTDAFLAVATQIFSS-------------------------------G-
ITWGKIVSLYAVAAGLAVDCV-RHAQPAMVHTIVDCLGEFV-RKTLVTWMKRRGGW----
-----SDITK----------------CVVNTDPNL------RSHW-L------------V
AAICSF-GHFLKAI--------------------------FFVLLPER------------
----
>T_rubripes_ENSTRUP00000018728
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEVLDVFDRS-LTEKELVSHSKA
LCRDYILSRLNQNGLGCSKAE-----------------------LNL-------------
-----------------------SPSSAALADASMVLLCLGDELESMQPSLYRNVARQLN
ISVAME----NMVSDAFIGVATEILST--------------------GTNQRFLTKIQG-
ITWGKVVSMYAVAGALAVDCV-RQGHATTVHILVDSLGQFV-RKFLVPWLKRRGGW----
-----ADISR----------------CVVKKDLAP------EHHW-L------------S
SSVESL-KYFLSTV--------------------------YVYIMKEA------------
----
>T_nigroviridis_ENSTNIP00000018321
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEVLDVFDRS-LTEKELVSHSKA
LCRDYILSRLTQSGLGWSKSE-----------------------LNL-------------
-----------------------SPSSTALADASMVLLCLGDELESMQPSLYRNVARQLN
ISVAME----NMVSDAFIAVATEILST-------------------------------G-
ITWGKVVSMYAVAGALAVDCV-RQGHPTTVHILVDSLGQFV-RRFLVPWLKRRGGW----
-----ADITR----------------CVVRKDLAP------EHHW-L------------F
SSVDSL-KYFLTTI--------------------------YVYIMKEA------------
----
>G_gallus_ENSGALP00000009257
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEVMEVFDRS-PTDKELVSQAKA
LCRDYINSRLIRAGVSWSKPE-----------------------HNT-------------
-----------------------PVPGGKLAEVSAILLCLGDELEYIRPNVYRNIARQLN
ISLHSE----TVVTDAFLAVAAQIFTA-------------------------------G-
ITWGKVVSLYAVAAGLAVDCV-RHAQPAMVHTIVDCLGEFV-RKTLVTWLKRRGGW----
-----ADITK----------------CVVSTDPSL------RSHW-L------------V
AAVCSF-GHFLKAI--------------------------FFVLLPER------------
----
>M_domestica_ENSMODP00000020066
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEVMEVFDRS-PTDKELVSQAKA
LGREYIHSRLIRAGLVWSKPE-----------------------AKT-------------
-----------------------PTPGGKLAEVASILLRLGDELEYIRPNVYRNIARQLN
ISLQSE----SVVTDAFLAVATQIFAA-------------------------------G-
ITWGKVVSLYAVAAGLAVDCV-KQAQPAMVHTIVDCLGEFV-RKTLVTWLKRRGGW----
-----ADIMK----------------CVVDSDPSL------RSHW-L------------V
AALCSF-GHFLKAI--------------------------FFVLLPER------------
----
>T_rubripes_ENSTRUP00000030263
---------------MEM------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAA---EVFDRS-PTDKELVSQAKA
LCRDYIHSRLNRAGVGWSKAD-----------------------HGL-------------
-----------------------AASGGTLGEVSSVLMWLGAELEYLRPNVYCNVARQLN
ITVASE----SIMSDAFLAVAADIFST--------------------EYILR--QRYEG-
VTWGKVVSLYAVAGALAVDCV-RHGHPAMIHTIVDCMGEFV-RKSLISWLKRRGGW----
-----VDVTK----------------CVVNTDPNF------HSHW-L------------M
SALCAF-GNYLKTT--------------------------VLYLLREK------------
----
>G_aculeatus_ENSGACP00000006084
---------------MDM------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAA---EVFDRS-PTDKELVSQAKA
LCRDYIHSRLNRAGMGWSKPE-----------------------SGR-------------
-----------------------AAPGGGLGDVSSALLWLGDELEYLRPNVYRNVARQLN
ITVASE----SIVSDAFLAVAADIFST-------------------------------G-
VTWGKVVSLYAVAGALAVDCV-RHGHPAIVHTIVDCMGEFV-RKSLTTWLKRRGGW----
-----VDVTK----------------CVVNTDPSF------RSHW-L------------V
SAVCAF-GHYLKAT--------------------------VLYLLRDT------------
----
>G_aculeatus_ENSGACP00000018053
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRPSVMAAEVLDVFDRS-LTEKELVSQSKA
LCRDYILSRLHQNGQGWSKTE-----------------------LHL-------------
-----------------------SPSSAALAEVSLVLLCLGDELESIRPSLYRNVARQLN
ISVAME----NMVSDAFIGVATEIFST-------------------------------G-
ITWGKVVSMYAVAGALAVDCV-RQGHPATVHILVASLGQFV-RKFLVPWLKRRGGW----
-----AEMCK----------------CVLKKDLPP------EHHW-L------------S
SAMDSL-KYFLTAL--------------------------YVCVMKEP------------
----
>B_taurus_ENSBTAP00000011478
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEIMDAFDRS-PTDKELVAQAKA
LGREFVHARLLRAGLSWSAPE-----------------------RAA-------------
-----------------------PVPGGRLAEVCAVLLRLADELELIRPSVYRNVARQLN
LSLQSE----TVVTDAFLAVATQIFSA-------------------------------G-
ITWGKVVSLYSVAAGLAVDCV-RQAQPALVHALVDCLGEFV-RKTLATWLRRRGGW----
-----TDVLK----------------CVVSTDPGL------RSHW-L------------V
AALCSF-GRFLKAA--------------------------FFMLLPER------------
----
>T_nigroviridis_ENSTNIP00000005841
---------------MEM------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSMFAA---EVFDRS-PTDKELVSQAKA
LCRDYIHSRLNRAGIGWSKAE-----------------------NGP-------------
-----------------------PASGGTLGEASAVLLWLGDELEHLRPNVYCNVARQLN
ITVASE----SIMSDAFLAVAADIFST-------------------------------G-
VTWGKVVSLYAVAGALAVDCV-RHGHPAMVHTIVDCMGEFV-RKSLTSWLKRRGGW----
-----VDVTR----------------CVVNTNPNF------DSHW-L------------V
SALRAF-GSYLKAT--------------------------VLYLLREK------------
----
>M_musculus_ENSMUSP00000027499
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEIMDAFDRS-PTDKELVAQAKA
LGREYVHARLLRAGLSWSAPE-----------------------RAS-------------
-----------------------PAPGGRLAEVCTVLLRLGDELEQIRPSVYRNVARQLH
IPLQSE----PVVTDAFLAVAGHIFSA-------------------------------G-
ITWGKVVSLYSVAAGLAVDCV-RQAQPAMVHALVDCLGEFV-RKTLATWLRRRGGW----
-----TDVLK----------------CVVSTDPGF------RSHW-L------------V
ATLCSF-GRFLKAA--------------------------FFLLLPER------------
----
>R_norvegicus_ENSRNOP00000024693
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEIMDAFDRS-PTDKELVAQAKA
LGREYVHARLLRAGLSWSAPE-----------------------RAS-------------
-----------------------PAPGGRLAEVCTVLLRLGDELEQIRPSVYRNVARQLH
IPLQSE----PVVTDAFLAVAGHIFSA-------------------------------G-
ITWGKVVSLYSVAAGLAVDCV-RQAQPAMVHALVDCLGEFV-RKTLATWLRRRGGW----
-----TDVLK----------------CVVSTDPGF------RSHW-L------------V
ATLCSF-GRFLKAA--------------------------FFLLLPER------------
----
>O_latipes_ENSORLP00000020538
---------------MDV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEVLDVFERS-LSEKELVTQSKA
LCRDYILSRLHQNGMGWSKAE-----------------------INF-------------
-----------------------SPSNAALSEVTMVLLCLGDELECIQPGLYRNVARQLN
ISVAME----NVVSDAFLGVATEIFSA--------------------VFSAKTQQTDSI-
ITWGKVVSMYAVAGALAVDCV-RQGYLTTVHILVDSLGQFV-RKFLVHWLKRRGGW----
-----AEITK----------------CVVKKELTS------EQPW-L------------S
SIMESV-KYALTTL--------------------------YVYVMKET------------
----
>H_sapiens_ENSP00000314132
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEIMDAFDRS-PTDKELVAQAKA
LGREYVHARLLRAGLSWSAPE-----------------------RAA-------------
-----------------------PVP-GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLH
ISLQSE----PVVTDAFLAVAGHIFSA-------------------------------G-
ITWGKVVSLYAVAAGLAVDCV-RQAQPAMVHALVDCLGEFV-RKTLATWLRRRGGW----
-----TDVLK----------------CVVSTDPGL------RSHW-L------------V
AALCSF-GRFLKAA--------------------------FFVLLPER------------
----
>G_gorilla_ENSGGOP00000015296
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEIMDAFDRS-PTDKELVAQAKA
LGREYVHARLLRAGLSWSAPE-----------------------RAA-------------
-----------------------PVP-GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLH
ISLQSE----PVVTDAFLAVAGHIFSA-------------------------------G-
ITWGKVVSLYAVAAGLAVDCV-RQAQPAMVHALVDCLGEFV-RKTLATWLRRRGGW----
-----TDVLK----------------CVVSTDPGL------RSHW-L------------V
AALCSF-GRFLKAA--------------------------FFVLLPER------------
----
>M_mulatta_ENSMMUP00000007481
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEIMDAFDRS-PTDKELVAQAKA
LGREYVHARLLRAGLSWSAPE-----------------------RAA-------------
-----------------------PVP-GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLH
ISLQSE----PVVTDAFLAVAGHIFSA-------------------------------G-
ITWGKVVSLYAVAAGLAVDCV-RQAQPAMVHALVDCLGEFV-RKTLATWLRRRGGW----
-----TDVLK----------------CVVSTDPGL------RSHW-L------------V
AALCSF-GRFLKAA--------------------------FFVLLPER------------
----
>P_pygmaeus_ENSPPYP00000014939
---------------MEV------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LRRSSVFAAEIMDAFDRS-PTDKELVAQAKA
LGREYVHARLLRAGLSWSAPE-----------------------RAA-------------
-----------------------PVP-GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLH
ISLQSE----PVVTDAFLAVAGHIFSA-------------------------------G-
ITWGKVVSLYAVAAGLAVDCV-RQAQPAMVHALVDCLGEFV-RKTLATWLRRRGGW----
-----TDVLK----------------CVVSTDPGL------RSHW-L------------V
AALCSF-GRFLKAA--------------------------FFVLLPER------------
----
>O_latipes_ENSORLP00000002641
---------------LES------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MRACGVARVNPAQAFSRSAPTDKELVSQAKA
LCREYIHSRLNRAGIGWSKPE-----------------------HAQ-------------
-----------------------AGAGGALGEVSSVLLWLGEELEYLRPNVYRNVARQLN
ITVASE----SIVSDAFLAVAADIFST-------------------GRISEKQNHCHKR-
ITWGKVVSLYAVAGALAVDCV-RHGHPAMVHTIVDCMGEFA-RKSLTVWLKKRGGW----
-----VDMTK----------------CVVNTDPSF------HSHW-L------------L
AAVCAF-GHYLKAV--------------------------VLHLLREK------------
----
>E_caballus_ENSECAP00000000132
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------DELELIRPSVYRNVARQLN
ISLQSE----TVVTDAFLAVSAQIF-A-------------------------------G-
ITWGKVVSLYLVAAGLAVDCV-RQAQPAMVHALVDCLGEFV-RKTLATWLRRRGGW----
-----TDVLK----------------CVVSTDPGY------RSHW-L------------V
AAFCSV-GRFLKAA--------------------------FFMLLPER------------
----
>D_melanogaster_FBpp0087182
---------------MPGTSYPTNNDNFSNGFPMATTQSERL-LQAQNRRKFSFPATL--
------------------------------------------------------------
-------------------------------------------------HSASLLEVGGG
--------PKET---TRRRLSNVSDAVTRK------LSYTIGWKAAQ-IPAQDIISQGRC
LCGHYIKRRLRRSGLFNKKLG-----------------------LQRIRSILG-------
-----------------------STSMGIVRDVFPAVQVLGDELERMHPRIYNGVARQIC
RNPGGEFHTPDAVSLLLGAVGRELFRV-------------------------------E-
ITWSKVISLFAIAGGLSVDCV-RQGHPEYLPKLMESVSEVI-EDELVPWINENGGW----
-----SGINT----------------HVLPTTNSL-----NPLEW-T------------T
LVIGVVFGLILVFM--------------------------ILRFIFNLIV----PKIYQR
FTNS
>D_melanogaster_FBpp0085443
---------------MAPTTSPPP-----KLAKFKSSSLDHEIYTANRRGTIATASSD--
------------------------------------------------------------
-------------------------------------------------WKALRGGVGGG
-----AGGPGSVPNPSNGRSLHAGGPMTRAASTSSLASSTRTMTNYQ-EYKMDIINQGKC
LCGQYIRARLRRAGVLNRKV------------------------TQRLRNILD-------
-----------------------PGSSHVVYEVFPALNSMGEELERMHPRVYTNISRQLS
RAPFGELEDSDMAPMLLNLVAKDLFRS-------------------------------S-
ITWGKIISIFAVCGGFAIDCV-RQGHFDYLQCLIDGLAEII-EDDLVYWLIDNGGW----
-----LGLSR----------------HIRPRVGEF-----TFLGW-L------------T
LFVTISAGAYMVSN--------------------------VCRRIGGQLY----SLLF--
----
>A_aegypti_AAEL001521-PA
---------------MLSAEAPVSHNHHLLPDRLSA--------PALARRKFSFPANL--
------------------------------------------------------------
-------------------------------------------------HSTVLHGDPPG
SINSGSLQPSSTASFARRRLSNVSDVVTRK------LSSTIGWKQPV-LPSQDIITQGKC
LCGQYIRCRLKKSGVFNRKLG-----------------------LQRIRSIVG-------
-----------------------TPTIHVVREVFPALLSVGEELERMYPRVYNGVARQLS
RIGRGELKTPETAPVLLSAIARDLFRS-------------------------------D-
ITWGKVVSLFAIAGGLSVDCV-RQGHPDYLPKLIEGVADVI-EDELVTWISENGGW----
-----VGLAN----------------KVRPPQEEI-----TFAGR-C------------F
VGAGLLVFFKKDRT--------------------------PQKFLINLHLQSKQNREDQS
DLEV
>A_gambiae_AGAP011552-PA
---------------MSSTAG--------------AFHQQHQPQQQSPRSPIVAAAVA--
------------------------------------------------------------
-------------------------------------------------AAAAIGAVSGG
-----SA--GGVVG----------------------WTNKRSPIHHL-TTSQDVINQGKC
LCGEYIRARLKRSGLLNRKI------------------------LQRLRNSMEHCMAGSG
G----------------------LGGGAVVREALPILNGMGEELERMHPRLYSNVSRQIS
NEPWGELTEPDTVGYLLHVVAKDLFKS-------------------------------G-
ITWGKVISLFAIAGGLAVDCV-RQDHADYLQQLIEGTADVI-EEDLSGWLVERGGW----
-----LGLQD----------------HVHPPQPEI-----SVTGW-V------------S
ITALTLAVIYIVSL--------------------------FLRVIGSGYAEPERSTN---
----
>A_aegypti_AAEL001515-PA
---------------MEMTSP---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------TLANNFANVWTNRRSPIHHL-TTTQDVINQGKC
LCGEYIRARLRRSGLLNRKI------------------------LQRLRSTME-------
-----------------------VPNCVVVRETSPILNGMGEELERMHPRLYTNVSRQIS
VEPWGELTEPDSVCYLLHIVAKDLFKT-------------------------------D-
ITWGKVISLFAIAGGLAVDCV-RQEHYDYLQQLIEGTTDVI-EEDLSLWLVEKGGW----
-----LGLHD----------------HVHPPQTEI-----TFLGW-M------------A
ITISTLFVIYLISV--------------------------LLKYLGSSYL----SKI---
----
>C_intestinalis_ENSCINP00000016140
---------------MTS-HESENASGFLKPEMESQRRHSWDGRFSTNKIDLGGESTVCR
NDSKGRRRRELRRSHVVTEAPDVTLFEEQDQNNASTIPTKDDPTPVASENKNTNNRPWGL
RRRITKTENHCEKIEDSTPANQTGTPKRRSGIASFATGSSPRNLWQPQKPSVRFTDVNDS
NINAATPPDMSSRSFRNRRATVHYSSTGRPSVM---ERRHPARIALE-AKEGKALEQTKD
ICKDYIVHRLQQRKLANRVKV-----------------------TRQ-------------
--------------------------QSASRALSRDVIFIASELERMQKHLYSDVSKQIG
ITLRSE----DVLRKVFFELAGEILTTEPVTIPKEATVNGETKKEKSRAFVSSGSRIIE-
ITWGRICAVVAIAGGLSIDCV-NQGHSDLVNQLIEFCGEFASEEGVLRWIVSQGGW----
-----ETLRE----------------MTDDHSASH-----TANDYGY------------L
THICNV-ALALTAC--------------------------TLATVLSVV-----AIASVS
DTAG
>C_intestinalis_ENSCINP00000019812
---------------MTSYTSDVNHNSIYETERKNKRTLLADNINSI-------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MRDSVTFVTSSIADLTSSCVSLGDDSVFNS-TSYEEDVRLTTG
ICRDYICYRLKRDGFGERVTV-----------------------TEH-------------
-------------------------APAHNHNLSNKILNLGSGFERMFPKSFRQISRQIG
YVFSSE----ATVRRLYFRMGVHIMGV----------------------------VECN-
YTWGRILSLLGLAGAMAVDCI-SQGHPELAESMIGISSDFI-QRNALDWIIKHGGW----
-----GGLVD----------------NFSPKPMKSYWSTRNILKW-N------------G
GVTLAV-FILLFAL--------------------------MLAILPRLK-----TNDN--
----
>G_aculeatus_ENSGACP00000018700
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MASHPGGGDQGNNKDQILELGTV
LLKDFIFERVKRHGDSTETVT-----------------------RTQLGGV---------
-----------------------ELSDPNHKKLAMCLQQIGDELD-------GNVELQRM
MNDSSL----GPTKDVFLKVAFEIFSD-------------------------------GK
FNWGRVVALFYFACRLVIKAL-VTKVPDIIRTIISWTMDYL-REHVINWIREQGGW----
-----EGIRS----------------------------HLGTPTW-Q------------T
VGVFLA-GVLTTVL--------------------------VIRKM---------------
----
>H_sapiens_ENSP00000293288
---------------MD-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------GSGEQP-RGGGPTSSEQIMKTGAL
LLQGFIQDRAGRMGGEAPELA-----------------------LDP-------------
-----------------------VPQDASTKKLSECLKRIGDELD-------SNMELQRM
IAAVDT----DSPREVFFRVAADMFSD-------------------------------GN
FNWGRVVALFYFASKLVLKAL-CTKVPELIRTIMGWTLDFL-RERLLGWIQDQGGW----
-----VRLLKPPHPHHRALTTAPAPPSLPPATPLGPWAFWSRSQW-C------------P
LPIFRSSDVVYNAF--------------------------SLRV----------------
----
>G_aculeatus_ENSGACP00000018978
---------------MADGGREKQDDG---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------DREPRGAEGGEDVVDDPIMEQGAV
VLRGYVVSRINAEDPSRHVS------------------------PEQLGGRPN-------
-----------------------EHQDPQIKEVVKQLMKIADEMN-------RNAELQRL
ISQVPG----NCAQDIFMKVAKSIFDD-------------------------------G-
INWGRVVALFHLAYRLIYRAL-TTNHLENIRIIIGWVLRFI-RERLYPWLVQQGGW----
-----VGVIN------------------------------GFSRW-R------------N
VAIVAS-VALVVAL--------------------------VYYRKTR-------------
----
>X_tropicalis_ENSXETP00000050759
---------------MATHGAGGDYPGEDKEKNQGEGGAAGGP-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------SLGAAGDRSGTGVSTEQILETGEL
LLNGFISDRLQNNPDVAGARA-----------------------LFP-GST---------
-----------------------QHSDPSIKRLSECLRKIGDELD-------ANIELQRR
IECVPC----NSPKQVFFHVAKELFAD-------------------------------GV
FNWGRVVALFYFACKLVVKAL-CTKVPEMIRTIINWTMEYL-REYVVQWIRDQGGW----
-----EGMLS----------------------------YFGTPTW-Q------------T
VGVFLA-GVLTATI--------------------------AIWKMS--------------
----
>T_rubripes_ENSTRUP00000014135
---------------MS-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------QNRE
LVIFYIKYKLSQRNYPFNHNGLILEPPSRTDG---------QFVTTQFNGTF---NGASP
GTPPATSL------------------ATSLDTVKEALRDTGNEFELRYTCAFSDLHNQLH
ITP-------ATAYQSFENVMDEVFRD-------------------------------G-
VNWGRIVGLFAFGGALCVECV-EKEMSPLVGRIIEWMTVYL-DNHIQPWIQSQGGW----
-----VRFAE---------------LFGQDAAAESRRSQERFRNG-L------------L
VGMSLAAGIAIGSF--------------------------IVRKLL--------------
----
>A_carolinensis_ENSACAP00000011187
---------------MSS------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRA
LVVDFLSYKLSQRGHSWHEIE-------MESG------EEAMEPANETGNTL---NGSPS
WHPSPSHV--INGASEHPELLEEEEEENPRVDVSQTLREAGDEFELRYRRAFSDLTSQLH
ITL-------GTAYQSFEQVVNELFHD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMQGLVVRIASWMTTYL-TEHLDPWIQENGGW----
-----ERFVD---------------VYGNDAAAKSRKGQERFNKW-L------------W
TGATVAGVVLLGSL--------------------------LSRK----------------
----
>T_guttata_ENSTGUP00000006866
---------------MYS------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVIDFVSYKLSQKGYSWSQLE--EEDENRTDF---------AGEEDEMDGVL---NGSPS
WHAATSHI--VNGATVHQNSL-EVHEIRRAADVRQALREAGDEFELRYRRAFSDLTSQLH
ITP-------STAYQSFEQVVNELFRD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-VKEMRVLVKRIVSWMTTYL-TDHLDPWIQENGGW----
-----ERFVD---------------SM-NDAAAEMRKGQE-FNKW-L------------L
TGATVAGVLLLGSL--------------------------LSRK----------------
----
>D_rerio_ENSDARP00000089067
---------------MADGKNGETTD----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------ENELKGATGGEDVVDDAIIEQSAV
LLRGYVIQQATIDDPNIHVS------------------------HETLGGRPQ-------
-----------------------DEEDPQIKEVVDQLLKIADDLN-------KNAELQHL
ISTVQS----NCAQDVFMTVARSIFDD-------------------------------G-
INWGRVVALFHLAYRLIFQAL-TQNHLEIIKNIISWFLQFM-KKHISAWIRQQGGW----
-----EGIFR------------------------------SMTRW-R------------T
VSTIAA-VAFIVAV--------------------------VYWRRTR-------------
----
>D_rerio_ENSDARP00000095258
---------------MSY------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------YNRE
LVVFFIKYKLSQRNYPCNHIG-LTEDTNRTDGAEENG-EGAAGATTLVNGTMNRTNASST
GTPPQSPASSPQRQ---------TNGSGGLDAVKEALRDSANEFELRYSRAFNDLSSQLH
ITP-------ATAYQSFESVMDEVFRD-------------------------------G-
VNWGRIVGLFAFGGALCVECV-EKEMSPLVGRIAEWMTVYL-DNHIQPWIQSQGGW----
-----ERFAE---------------IFGKDAAAESRKSQESFKKW-L------------F
AGMTLLTGVVVGGL--------------------------IAQKRL--------------
----
>T_nigroviridis_ENSTNIP00000007577
RSHPGAKSKGASTQRMS-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------LNRE
LVIFYIKYKLSQRNYPLSH---IVEPSSRTEG---------QFGTTQSNGTF---NGASP
GTPPAPSQ-----H---------QQSLTSLDAVKEALRDTGNEFELRYTCAFSDLHNQLH
ITP-------ATAYQSFENVMDEVFRD-------------------------------G-
VNWGRIVGLFAFGGALCVECV-EKEMNPLVGRIIEWMTVYL-DNHIQPWIQSQGGW----
-----ERFAE---------------LFGQDAAAESRRSQERFRNG-L------------F
LGMSLAAGIALGSF--------------------------IVMR----------------
----
>R_norvegicus_ENSRNOP00000040259
---------------MSQ------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVVDFLSYKLSQKGYSWSQFS--DVEENRTEA------PEETEPERETPSAI---NGNPS
WHLADSPA--VNGATGHSSSL-DAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLH
ITP-------GTAYQSFEQVVNELFRD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMQVLVSRIASWMATYL-NDHLEPWIQENGGW----
-----VRTTP---------------LVCPPLVCLSSVEIPNCPFWSPGMVVEDIDYSGDI
PGFTLIPGVNFGNIDDPVFKEPVFFILATLVAPQFHSFVPISRQRKTACVFTWLKT----
----
>M_mulatta_ENSMMUP00000005209
---------------MD-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------GSGEQP-RGGGPTSSEQIMKTGAL
LLQGFIQDRAGRMGGETPELA-----------------------LDP-------------
-----------------------VPQDASTKRLSECLKRIGDELD-------SNMELQRM
IAAVDT----DSPREVFFRVAADMFSD-------------------------------GN
FNWGRVVALFYFASKLVLKAL-CTKVPELIRTIMGWTLDFL-RERLLGWIQDQGGW----
-----DGLLS----------------------------YFGTPTW-Q------------T
VTILVA-GVLTASL--------------------------TIWKKMG-------------
----
>B_taurus_ENSBTAP00000008572
---------------MSQ------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVVDFLSYKLSQKGYSWSQFS--DVEENRTEA------PEGTESDMETPSAI---NGNAS
WHLADSPA--VNGATGHSRSS-DAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLH
ITP-------GTAYQSFEQVVNELFRD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMQVLVSRIATWMATYL-NDHLEPWIQENGGW----
-----DTFVE---------------LYGNNAAAESRKGQERFNRW-F------------L
TGMTVAGVVLLGSL--------------------------FSRK----------------
----
>M_mulatta_ENSMMUP00000007865
---------------MSQ------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVVDFLSYKLSQKGYSWSQFS--DVEENRTEA------PEGTESEMETPSAI---NGNPS
WHLVDSPA--VNGATGHSSSL-DAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLH
ITP-------GTAYQSFEQVVNELFRD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMQVLVSRIAAWMATYL-NDHLEPWIQENGGW----
-----DTFVE---------------LYGNNAAAESRKGQERFNRW-F------------L
TGMTVAGVVLLGSL--------------------------FSRK----------------
----
>B_taurus_ENSBTAP00000017739
---------------MD-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------GSGEQP-RGGGPTSSEQIMKTGAL
LLQGFIQDRAGRMGGETPELG-----------------------LEQ-------------
-----------------------VPQDASTKKLSECLKRIGDELD-------SNMELQRM
IAAVDT----DSPREVFFRVAAEMFSD-------------------------------GN
FNWGRVVALFYFASKLVLKAL-CTKVPELIRTIMGWTLDFL-RERLLGWIQDQGGW----
-----DGLLS----------------------------YFGTPTW-Q------------T
VTIFVA-GVLTASL--------------------------TIWKKMG-------------
----
>M_domestica_ENSMODP00000017160
---------------MD-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------GSGEQPRGGAGATSSEQIMRTGAV
LLQGFIQDRAGRVAGGAPELL-----------------------LDSMGDSAP-------
-----------------------LPSDPRTKRLTECLRRIGDELD-------SNMELQRM
IAAVET----DSPREVFFRVAAEMFSD-------------------------------GN
FNWGRVVALFYFASKLVLKAL-CTKVPELIRTIVGWTLDFL-RERLLTWIQEQGGW----
-----V------------------------------------------------------
------------------------------------------------------------
----
>G_gallus_ENSGALP00000010059
---------------MSS------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVIDFVSYKLSQRGHCWSELE--EEDENRTDT----------AAEAEMDSVL---NGSPS
WHPPAGHV--VNGATVHRSSL-EVHEIVRASDVRQALRDAGDEFELRYRRAFSDLTSQLH
ITP-------GTAYQSFEQVVNELFHD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMRVLVGRIVSWMTTYL-TDHLDPWIQENGGW----
-----ERFVD---------------LYGNNAAAELRKGQETFNKW-L------------L
TGATVAGVLLLGSL--------------------------LSRK----------------
----
>T_rubripes_ENSTRUP00000032199
---------------MSY------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------NNRE
LVEHFLRYKLSQRNYPTSLLR-PEDTDGRTEG------------EKRSPGAS---NGLLV
RSRNRGGA-----S---------PSAGAGIEAVNAALRDSAEEFEKLFAQAFSDLSSQLD
ITP-------DTAYQSFKNVMDEVFKD-------------------------------G-
VNWGRVVGLFAFGGVLCVECV-EKDASQLVCRIADWMTIYL-DEHINPWIQSQGGW----
-----DCFAK---------------IFGDDAAAEGRRARENLSRW-M------------L
GGLALLMGVLVGAF--------------------------IVKKH---------------
----
>E_caballus_ENSECAP00000014770
---------------MSQ------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVVDFLSYKLSQKGYNWSQFS--DVEENRTEA------PEGTESEMETPSAI---NGNPS
WHLADSPT--GNGATGHSSSL-DAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLH
ITP-------GTAYQSFEQVVNELFRD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMQVLVSRIATWMATYL-NDHLEPWIQENGGW----
-----DTFVE---------------LYGNNAAAESRKGQERFNRW-F------------L
TGMTVAGVVLLGSL--------------------------FSRK----------------
----
>C_familiaris_ENSCAFP00000010478
---------------MSQ------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVVDFLSYKLSQKGYSWSQFS--DVEENRTEA------PEGTESEMETPSAI---NGNPS
WHLADSPA--VNGATGHSSSL-DAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLH
ITP-------GTAYQSFEQVVNELFRD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMQVLVSRIAAWMATYL-NDHLEPWIQENGGW----
-----DTFVE---------------LYGNNAAAESRKGQERFNRW-F------------L
TGMTVAGVVLLGSL--------------------------FSRK----------------
----
>H_sapiens_ENSP00000365230
---------------MSQ------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVVDFLSYKLSQKGYSWSQFS--DVEENRTEA------PEGTESEMETPSAI---NGNPS
WHLADSPA--VNGATGHSSSL-DAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLH
ITP-------GTAYQSFEQVVNELFRD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMQVLVSRIAAWMATYL-NDHLEPWIQENGGW----
-----DTFVE---------------LYGNNAAAESRKGQERFNRW-F------------L
TGMTVAGVVLLGSL--------------------------FSRK----------------
----
>P_pygmaeus_ENSPPYP00000012163
---------------MSQ------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVVDFLSYKLSQKGYSWSQFS--DVEENRTEA------PEGTESEMETPSAI---NGNPS
WHLADSPA--VNGATGHSSSL-DAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLH
ITP-------GTAYQSFEQVVNELFRD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMQVLVSRIAAWMATYL-NDHLEPWIQENGGW----
-----DTFVE---------------LYGNNAAAESRKGQERFNRW-F------------L
TGMTVAGVVLLGSL--------------------------FSRK----------------
----
>P_troglodytes_ENSPTRP00000022903
---------------MSQ------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVVDFLSYKLSQKGYSWSQFS--DVEENRTEA------PEGTESEMETPSAI---NGNPS
WHLADSPA--VNGATGHSSSL-DAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLH
ITP-------GTAYQSFEQVVNELFRD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMQVLVSRIAAWMATYL-NDHLEPWIQENGGW----
-----DTFVE---------------LYGNNAAAESRKGQERFNRW-F------------L
TGMTVAGVVLLGSL--------------------------FSRK----------------
----
>T_rubripes_ENSTRUP00000036334
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------SDPNHKKLAQCLQKIGDELD-------GNMELQRM
INDSAL----KPTKDMFMKVALEIFSD-------------------------------GK
FNWGRVVALFYFACRLVIKAL-VTHVPDIIRTIISWTMDYL-QEHVVNWIREQGGW----
-----VR-----------------------------------------------------
------------------------------------------------------------
----
>O_latipes_ENSORLP00000021005
---------------MAN------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------VSNRS
IVEKYICHKLSKRGYVCGLNG-----------------------GQRENAANNGSVGDHS
-----------------------PTPADPLADIHRVLREAGDELERLYQRDFTEMSRQLY
LTS-------TTAKTRFAEVIDELFRD-------------------------------G-
VNWGRIIAFFEFGGTVCVECASNEEMSTQVASIAEWMTEYL-NGPLNSWIEENGGW----
-----MCRLG---------------LFGKKRAVYRFEYPKTSSRW-C------------C
AIHSLIAGSKLPLE--------------------------LAAR----------------
----
>O_cuniculus_ENSOCUP00000002775
---------------MSQ------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVVDFLSYKLSQKGYSWSQFS--DVEENRTEA------PEGTGPEMETPSAI---NGNPA
WHPADSPA--VNGATGHSSSL-DAREVIPMTAVKQALREAGDEFELRYRRAFSDLTSQLH
ITP-------GTAYQSFEQVVNELFRD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMEVLVSRIAAWMATYL-NDHLEPWIQENGGW----
------------------------------------------------------------
------------------------------------------------------------
----
>M_musculus_ENSMUSP00000086454
---------------MSQ------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVVDFLSYKLSQKGYSWSQFS--DVEENRTEA------PEETEAERETPSAI---NGNPS
WHLADSPA--VNGATGHSSSL-DAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLH
ITP-------GTAYQSFEQVVNELFRD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMQVLVSRIASWMATYL-NDHLEPWIQENGGWGVSG
GTPLRSVFRR---------------LVQVPGVAEHVCDPSLWEVE--------------T
EGSEVQGPPQLL------------------------------------------------
----
>T_nigroviridis_ENSTNIP00000017211
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------DVVDDPILEQGAV
VLRGYVIERIHVEQPSLHVS------------------------SEDLGGRSE-------
-----------------------EQRDPQTKEVVEQLLKIADDLN-------RNAEFQHL
VSQVQG----NCAQDVFMQVARSIFAD-------------------------------G-
INWGRVVALFHLAYRLILKAL-TTNHLENIRTVIGWVLQVI-REQLYSWLVQQGGW----
-----AGVIQ------------------------------RFARW-R------------V
AAVVAS-VLLVGMF--------------------------VYYRRTR-------------
----
>M_musculus_ENSMUSP00000033093
---------------MD-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------GSGEQL-GSGGPTSSEQIMKTGAF
LLQGFIQDRAGRMAGETPELT-----------------------LEQ-------------
-----------------------PPQDASTKKLSECLRRIGDELD-------SNMELQRM
IADVDT----DSPREVFFRVAADMFAD-------------------------------GN
FNWGRVVALFYFASKLVLKAL-CTKVPELIRTIMGWTLDFL-RERLLVWIQDQGGW----
-----EGLLS----------------------------YFGTPTW-Q------------T
VTIFVA-GVLTASL--------------------------TIWKKMG-------------
----
>G_aculeatus_ENSGACP00000005643
---------------MS-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------QNRE
LVVFYINYKLSQRNLPLNHIG-LSEPPNRTGGGVEAGAAGGQRGATHSNGTF---NGTSP
GTPPASPL--LQQR---------SPSTASLDAVKEALRDSANEFELRYARAFSDLHNQLH
ITP-------ATAYQSFEDVMDEVFRD-------------------------------G-
VNWGRIVGLFAFGGALCVECV-DKEMSPLVGRIVEWMTLYL-DNHIQPWIQNQGGW----
-----RSDI---------------------------------------------------
------------------------------------------------------------
----
>R_norvegicus_ENSRNOP00000028328
---------------MD-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------GSGDHL-GGGGPTSSEQIMKTGAF
LLQGFIQDRAERMAGETPELT-----------------------LEQ-------------
-----------------------PPQDASTKKLSECLRRIGDELD-------NNMELQRM
IADVDT----DSPREVFFRVAADMFAD-------------------------------GN
FNWGRVVALFYFASKLVLKAL-CTKVPELIRTIMGWTLDFL-RERLLVWIQDQGGW----
-----DGLLS----------------------------YFGTPTW-Q------------T
VTIFVA-GVLTASL--------------------------TIWKKMG-------------
----
>M_domestica_ENSMODP00000024313
---------------MSH------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SNRE
LVIDFLSYKLSQKGYNWSQFE--D--ENRTEV------LEGA----EIPSTV---NGSPS
WHPADSRA--VSGATGHSSSL-DAHETIPVAAVKQALREAGDEFELRYRRAFSDLTSQLH
ITP-------GTAYQSFEQVVNELFRD-------------------------------G-
VNWGRIVAFFSFGGALCVESV-DKEMEVLVGRITSWMATYL-DDHLDPWIQENGGW----
-----DTFVE---------------LYGNDAAAESRKGQERFNRW-L------------L
TGMTVAGVVLLGSL--------------------------FSRK----------------
----